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virulizin

extracted from bovine bile by a standardized process including ethanol precipitation, column purification, heat reduction, ether extraction, and tyndallization, which removes most bile salts and large peptides. The drug contains 5% (w/v) solids and is comprised of inorganic (95-99% of dry weight) and organic compounds of molecular weights of <3,000 Daltons (1-5% of dry weight); original standardization by murine bioassay replaced by TNF-alpha assay;
Networked: 10 relevant articles (7 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jin, Hongnan: 7 articles (12/2008 - 03/2003)
2. Wang, Ming: 7 articles (12/2008 - 03/2003)
3. Young, Aiping H: 7 articles (12/2008 - 03/2003)
4. Feng, Ningping: 7 articles (12/2008 - 03/2003)
5. Wright, Jim A: 7 articles (12/2008 - 03/2003)
6. Lee, Vivian: 5 articles (12/2008 - 11/2003)
7. Lee, Yoon: 4 articles (12/2008 - 03/2005)
8. Li, Hui: 4 articles (12/2008 - 03/2005)
9. Du, Caigan: 4 articles (03/2005 - 03/2003)
10. Gu, Xiaoping: 3 articles (12/2008 - 03/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Pancreatic Neoplasms (Pancreatic Cancer)
3. Melanoma (Melanoma, Malignant)
4. Neoplasm Metastasis (Metastasis)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Cisplatin (Platino)
2. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3. Interleukin-17 (Interleukin 27)
4. Interleukin-12 (IL 12)
5. Cytokines
6. Messenger RNA (mRNA)
7. Fluorouracil (Carac)
8. Dacarbazine (DIC)
9. Carbon Monoxide
10. gemcitabine

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)