virulizin

extracted from bovine bile by a standardized process including ethanol precipitation, column purification, heat reduction, ether extraction, and tyndallization, which removes most bile salts and large peptides. The drug contains 5% (w/v) solids and is comprised of inorganic (95-99% of dry weight) and organic compounds of molecular weights of <3,000 Daltons (1-5% of dry weight); original standardization by murine bioassay replaced by TNF-alpha assay;

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Context: Research Results