bovine collectin-43 protein

a bovine serum protein with homology to bovine conglutinin; belongs to collectins (group III of the C-type lectins); amino acid sequence given in first source; GenBank X75912

Also Known As:

collectin-43 protein, bovine; CL-43; CL-43, bovine; collectin-43; collectin-43, bovine

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Lectins: 6782
    - C-Type Lectins: 976
      - Collectins: 143
        bovine collectin-43 protein: 5

Experts

1.	Guzhova, Irina V: 2 articles (06/2021 - 06/2018)
2.	Komarova, Elena Y: 2 articles (06/2021 - 06/2018)
3.	Margulis, Boris A: 2 articles (06/2021 - 06/2018)
4.	Nikotina, Alina D: 2 articles (06/2021 - 06/2018)
5.	Holmskov, Uffe: 2 articles (04/2005 - 01/2003)
6.	Alexeev, Dmitry: 1 article (06/2021)
7.	Efremov, Sergey: 1 article (06/2021)
8.	Kartsev, Viktor G: 1 article (06/2021)
9.	Leonova, Elizaveta: 1 article (06/2021)
10.	Pavlov, Rostislav: 1 article (06/2021)

Related Diseases

1.	Neoplasms (Cancer) 06/05/2018 - "Consequently, CL-43 was found to reduce colony formation and motility of HCT-116 in the appropriate assays suggesting its possible application in the exploration of biology of metastasizing tumors. " 06/05/2018 - "Importantly, CL-43 elevated the growth-inhibitory and cytotoxic activity of etoposide, cisplatin, and doxorubicin suggesting that the pro-drug has broad prospect for application in a variety of anti-tumor therapy schedules."
2.	Human Influenza (Influenza) 04/29/2005 - "In addition, RAK resembled CL-43 in its greater capacity to inhibit the infectivity of influenza A virus and to increase uptake of influenza by neutrophils."
3.	Endometritis 08/01/2010 - "In bovine endometritis, desmin, α-actin-2, heat-shock protein (HSP) 27, peroxiredoxin-6, luteinizing hormone receptor isoform 1, collectin-43 precursor, deoxyribonuclease-I (DNase-I), and MHC class I heavy chain (MHC-Ih) were up-regulated. "
4.	Colonic Neoplasms (Colon Cancer) 06/27/2021 - "Importantly, CL-43 reduced migration capacity, EMT-linked transcription factors, and increased content of epithelial marker E-cadherin in colon cancer cells of three lines, including one derived from a clinical sample. "
5.	Carcinoma (Carcinomatosis) 06/27/2021 - "To prove that inhibiting Hsp70 may reduce EMT efficiency, we treated cells with a CL-43 inhibitor of the HSF1 transcription factor, which lowered Hsp70 and HSF1 content in the control and induced EMT in carcinoma cells. "

Related Drugs and Biologics

1.	Transcription Factors (Transcription Factor)
2.	Protein Isoforms (Isoforms)
3.	Cadherins (E-Cadherin)
4.	LH Receptors (LH Receptor)
5.	Prodrugs
6.	Heat-Shock Proteins (Heat-Shock Protein)
7.	Etoposide (VP 16)
8.	Doxorubicin (Adriamycin)
9.	Desmin
10.	Deoxyribonuclease I (Nickase)

Related Therapies and Procedures

1.	Therapeutics