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LIGA 20

a semisynthetic GM1 ganglioside with N-dichloroacetylsphingosine; about ten times more potent than the natural GM2 in protecting neurons in culture against glutamate toxicity
Also Known As:
II3Neu5-AcGgOse4-2-d-erythro-1,3-dihydroxy-2-dichloroacetamide-4-trans-octadacene; LIGA-20; LIGA20; Acetamide, N-(1-(((O-(N-acetyl-alpha-neuraminosyl)-(2-3)-O-(O-beta-D-galactopyranosyl-(1-3)-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1-4))-O-beta-D-galactopyranosyl-(1-4)-beta-D-glucopyranosyl)oxy)methyl)-2-hydroxy-3-heptadecenyl)-2,2-dichloro-, (R-(R*,S*-(E)))-
Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Wu, Gusheng: 5 articles (09/2011 - 11/2005)
2. Ledeen, Robert W: 4 articles (09/2011 - 11/2005)
3. Lu, Zi-Hua: 2 articles (09/2011 - 11/2005)
4. Amin, Ruchi: 1 article (09/2011)
5. Kulkarni, Neil: 1 article (09/2011)
6. Ledeen, Robert: 1 article (11/2007)
7. Xie, Xin: 1 article (11/2005)
8. Wang, Jianfeng: 1 article (11/2005)
9. Meyenhofer, Markus F: 1 article (11/2005)
10. Wang, Yvette: 1 article (11/2005)

Related Diseases

1. Seizures (Seizure)
2. Parkinsonian Disorders (Parkinsonism)
3. Thrombosis (Thrombus)

Related Drugs and Biologics

1. Kainic Acid (Kainate)
2. Gangliosides
3. G(M1) Ganglioside
4. gangliotetraose

Related Therapies and Procedures

1. Intraperitoneal Injections