glycine-extended gastrin 17

a precursor form of gastrin; high concentrations of glycine-extended gastrin 17 were mitogenic for a gastrin-responsive human colon cancer cell line in vitro

Also Known As:

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Aghanejad, Ayuob: 1 article (01/2018)
2.	Fathi, Farzaneh: 1 article (01/2018)
3.	Khajeh, Shirin: 1 article (01/2018)
4.	Mehdipour, Tayebeh: 1 article (01/2018)
5.	Omidi, Yadollah: 1 article (01/2018)
6.	Tohidkia, Mohammad Reza: 1 article (01/2018)
7.	Baldwin, Graham S: 1 article (12/2002)
8.	Barnham, Kevin J: 1 article (12/2002)
9.	Hollande, Frederic: 1 article (12/2002)
10.	Norton, Raymond S: 1 article (12/2002)

Related Diseases

1.	Carcinogenesis 11/01/2001 - "The aim of our study was to determine whether continuous systemic infusion of glycine-extended gastrin(17) stimulated proliferation and accelerated carcinogenesis in the colorectal mucosa. " 11/01/2001 - "Glycine-extended gastrin(17) could thus potentially act as a promoter of carcinogenesis."
2.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2018 - "Phage display selection of fully human antibody fragments to inhibit growth-promoting effects of glycine-extended gastrin 17 on human colorectal cancer cells." 12/13/2002 - "Amidated gastrin 17 stimulates gastric acid secretion and the development of gastric carcinoids, whereas glycine-extended gastrin 17 stimulates proliferation of the colonic mucosa and the development of colorectal cancers. " 01/01/2018 - "Glycine-extended gastrin 17 (G17-Gly), a dominant processing intermediate of gastrin gene, has been implicated in the development or maintenance of colorectal cancers (CRCs). "
3.	Aberrant Crypt Foci 11/01/2001 - "Short term infusion of glycine-extended gastrin(17) stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa." 11/01/2001 - "The total number of aberrant crypt foci in intact rats treated with the procarcinogen azoxymethane plus glycine-extended gastrin(17) was increased by 48% compared to the value in controls treated with azoxymethane only (p = 0.01). " 11/01/2001 - "We conclude that short term administration of glycine-extended gastrin(17) to mature rats not only has a proliferative effect upon colonic mucosa, but also increases the number of aberrant crypt foci formed in the colorectal mucosa after treatment with azoxymethane. "
4.	Polyps 12/01/2000 - "Immunohistochemistry identified progastrin in 91%, glycine extended gastrin 17 in 80%, and amidated gastrin 17 in only 47% of polyps. "
5.	Carcinoid Tumor (Carcinoid) 12/13/2002 - "Amidated gastrin 17 stimulates gastric acid secretion and the development of gastric carcinoids, whereas glycine-extended gastrin 17 stimulates proliferation of the colonic mucosa and the development of colorectal cancers. "

Related Drugs and Biologics

1.	gastrin 17 (G 17)
2.	Immunoglobulin Fragments
3.	Gastrins
4.	Azoxymethane
5.	Calcibiotic Root Canal Sealer
6.	big gastrin

Related Therapies and Procedures

1.	Aftercare (After-Treatment)