amyloid beta-protein (17-42)

a component of diffuse amyloid deposits isolated from brains of patients with Alzheimer's disease; amino acid sequence given in first source

Also Known As:

Abeta 17-42; beta-amyloid peptide 17-42

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neuroblastoma 09/01/2002 - "Here, we demonstrate that treatment of cells with Abeta 17-42 leads to apoptosis in two human neuroblastoma cell lines, SH-SY5Y and IMR-32. "
2.	Alzheimer Disease (Alzheimer's Disease) 09/01/2002 - "We propose that Abeta 17-42 constitutes an additional toxic peptide derived from APP proteolysis and may thus contribute to the neuronal cell loss characteristic of Alzheimer's disease." 09/01/2002 - "Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis."