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amyloid beta-protein (17-42)
a component of diffuse amyloid deposits isolated from brains of patients with Alzheimer's disease; amino acid sequence given in first source
Also Known As:
Abeta 17-42; beta-amyloid peptide 17-42
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Amyloid: 36214
Amyloidogenic Proteins: 1587
Amyloid beta-Protein Precursor: 519
Amyloid beta-Peptides: 13994
amyloid beta-protein (17-42): 1
Membrane Proteins: 10078
Amyloid beta-Protein Precursor: 519
Amyloid beta-Peptides: 13994
amyloid beta-protein (17-42): 1
Peptides: 82426
Amyloid beta-Peptides: 13994
amyloid beta-protein (17-42): 1
Peptide Fragments: 373
amyloid beta-protein (17-42): 1
Experts
1.
Kusiak, John W
: 1 article (09/2002)
2.
Norton, Darrell D
: 1 article (09/2002)
3.
Wang, Xiantao
: 1 article (09/2002)
4.
Wei, Wanli
: 1 article (09/2002)
Related Diseases
1.
Neuroblastoma
09/01/2002 - "
Here, we demonstrate that treatment of cells with Abeta 17-42 leads to apoptosis in two human neuroblastoma cell lines, SH-SY5Y and IMR-32.
"
2.
Alzheimer Disease (Alzheimer's Disease)
09/01/2002 - "
We propose that Abeta 17-42 constitutes an additional toxic peptide derived from APP proteolysis and may thus contribute to the neuronal cell loss characteristic of Alzheimer's disease.
"
09/01/2002 - "
Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis.
"
Related Drugs and Biologics
1.
Caspase 8 (Caspase-8)
2.
Peptides (Polypeptides)