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tazarotene (Tazorac)

a topical acetylenic retinoid; a topical kerytolytic
Also Known As:
Tazorac; AGN 190168; AGN-190168; ethyl 6-(2-(4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate; 3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-, ethyl ester
Networked: 377 relevant articles (104 outcomes, 106 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Pillai, Radhakrishnan: 19 articles (09/2022 - 03/2017)
2. Stein Gold, Linda: 16 articles (06/2022 - 01/2013)
3. Lin, Tina: 14 articles (06/2021 - 07/2018)
4. Guenin, Eric: 13 articles (09/2022 - 06/2019)
5. Tanghetti, Emil A: 11 articles (08/2021 - 02/2002)
6. Tanghetti, Emil: 10 articles (06/2022 - 06/2004)
7. Feldman, Steven R: 9 articles (10/2022 - 02/2003)
8. Kircik, Leon: 9 articles (07/2022 - 07/2007)
9. Del Rosso, James Q: 8 articles (06/2022 - 10/2004)
10. Jacobson, Abby: 8 articles (06/2022 - 01/2020)

Related Diseases

1. Psoriasis (Pustulosis Palmaris et Plantaris)
2. Acne Vulgaris
3. Erythema
4. Hyperpigmentation
5. Lentigo (Lentiginosis)
04/01/2004 - "At week 24, when compared to vehicle, tazarotene resulted in a significantly greater incidence of patients achieving treatment success (over 50 percent greater improvement) and at least a 1 grade improvement in fine wrinkling, mottled pigmentation, pore size, lentigines, elastosis, irregular depigmentation, tactile roughness, coarse wrinkling and overall integrated assessment of photodamage. "
11/01/2002 - "Compared with the vehicle, at week 24 tazarotene resulted in a significantly greater incidence of patients achieving treatment success (>or=50% global improvement) and at least a 1-grade improvement in fine wrinkling, mottled hyperpigmentation, lentigines, elastosis, pore size, irregular depigmentation, tactile roughness, coarse wrinkling, and the overall integrated assessment of photodamage (P<.01). "
02/01/2005 - "Tazarotene cream was significantly more effective than vehicle in reducing fine wrinkles, mottled hyperpigmentation, lentigines, irregular depigmentation, apparent pore size, elastosis, tactile roughness, and an overall integrated assessment of photodamage. "
01/01/2014 - "Tazarotene cream 0.1% (TAZ) is a United States Food and Drug Administration-approved drug indicated for use in the mitigation of facial fine wrinkling, facial mottled hyper- and hypopigmentation, and benign facial lentigines when taken in conjunction with a comprehensive skin care and sun avoidance program. "
09/01/2006 - "The incidence of >or=1-grade improvement from baseline (on a scale of none, minimal, mild, moderate, or severe) was significantly greater with tazarotene plus hydroquinone than with tazarotene alone for lentigines (weeks 12-24, p<or=0.01) and mottled hyperpigmentation (week 16, p<or=0.05). "

Related Drugs and Biologics

1. Retinoids
2. halobetasol (ulobetasol)
3. Adrenal Cortex Hormones (Corticosteroids)
4. Tretinoin (Retinoic Acid)
5. calcipotriene (calcipotriol)
6. tazarotene (Tazorac)
7. Adapalene (Differin)
8. Gels
9. Ointments (Pastes)
10. Therapeutic Uses

Related Therapies and Procedures

1. Therapeutics
2. Gas Lasers
3. Aftercare (After-Treatment)
4. Microspheres (Microsphere)
5. Dye Lasers