A 73209

a nucleoside analog of the oxetanocin family, a class of compounds that inhibit viral DNA synthesis; structure given in first source

Also Known As:

1-(3',4'-bis(hydroxymethyl)-2'-oxetanyl)-5-methyluracil; A-73209; 2,4(1H,3H)-Pyrimidinedione, 1-(3,4-bis(hydroxymethyl)-2-oxetanyl)-5-methyl-, (2R-(2alpha,3beta,4alpha))-

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        A 73209: 1

Related Diseases

Infections

02/01/1994 - "Efficacy of A-73209, a potent orally active agent against VZV and HSV infections."
02/01/1994 - "A-73209 appears to be a potent and selective agent against varicella-zoster virus and herpes simplex virus infections."
02/01/1994 - "Against HSV-2 infections in mice, the efficacy of A-73209 ranged from equal to 1.7 times less active relative to acyclovir with oral dosing. "
02/01/1994 - "A-73209 produced efficacy superior to acyclovir against lethal systemic or intracerebral HSV-1 infections in mice. "

Related Drugs and Biologics

1.	Acyclovir (Aciclovir)