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CAM 123-6 antigen
highly specific to pulmonary adenocarcinoma
Also Known As:
CAM 123-6; cancer-associated mucin 123-6
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycoconjugates: 1353
Glycoproteins: 24834
Membrane Glycoproteins: 2252
Mucin-1: 3087
CAM 123-6 antigen: 3
Mucoproteins: 203
Mucins: 10505
Mucin-1: 3087
CAM 123-6 antigen: 3
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Glycoproteins: 24834
Membrane Glycoproteins: 2252
Mucin-1: 3087
CAM 123-6 antigen: 3
Mucoproteins: 203
Mucins: 10505
Mucin-1: 3087
CAM 123-6 antigen: 3
Membrane Proteins: 10078
Membrane Glycoproteins: 2252
Mucin-1: 3087
CAM 123-6 antigen: 3
Biological Factors: 2472
Biomarkers: 240291
Tumor Biomarkers: 15272
Carbohydrate Tumor-Associated Antigens: 355
Mucin-1: 3087
CAM 123-6 antigen: 3
Antigens: 143924
Epitopes: 19548
Carbohydrate Tumor-Associated Antigens: 355
Mucin-1: 3087
CAM 123-6 antigen: 3
Neoplasm Antigens: 6217
Carbohydrate Tumor-Associated Antigens: 355
Mucin-1: 3087
CAM 123-6 antigen: 3
Related Diseases
1.
Adenocarcinoma
01/01/1997 - "
In differentiating pulmonary adenocarcinoma from other lung cancer, the diagnostic accuracy of CAM 123-6 was 81% and that of CEA was 74%, although there was no significant difference between them.
"
01/01/1997 - "
Comparative studies of CAM 123-6 and carcinoembryonic antigen for the serological detection of pulmonary adenocarcinoma.
"
02/01/1994 - "
CAM 123-6 is a promising candidate as a serum tumor marker for pulmonary adenocarcinoma.
"
02/01/1994 - "
CAM 123-6 was more specific to pulmonary adenocarcinoma than carcinoembryonic antigen (CEA), but the sensitivity of CAM 123-6 for pulmonary adenocarcinoma was similar to that of CEA.
"
02/01/1994 - "
A new KL-6-associated molecule detected by a bimonoclonal bideterminant sandwich assay using the EH-123 antibody as a catcher and horseradish peroxidase-labeled KL-6 as a tracer was designated as CAM 123-6. In 59% (22 of 37) of patients with pulmonary adenocarcinoma, serum levels of CAM 123-6 were abnormally elevated and the positive rate increased with the progression of clinical stage.
"
2.
Lung Diseases (Lung Disease)
01/01/1994 - "
In benign lung diseases, however, LISA 1-6 and CAM 123-6 were increased abnormally at the rates of only 5.3% and 0% respectively.
"
01/01/1997 - "
For discriminating lung cancer from benign lung disease, the combination of CAM 123-6, SCC, and NSE showed 64% diagnostic accuracy, and the combination of CEA, SCC, and NSE 65%.
"
01/01/1994 - "
KL-6 was increased abnormally at high rates of more than 50% in pancreatic cancer and in benign lung diseases, LISA 1-6 only in pancreatic cancer, and CAM 123-6 only in pulmonary adenocarcinoma.
"
3.
Pancreatic Neoplasms (Pancreatic Cancer)
01/01/1994 - "
KL-6 was increased abnormally at high rates of more than 50% in pancreatic cancer and in benign lung diseases, LISA 1-6 only in pancreatic cancer, and CAM 123-6 only in pulmonary adenocarcinoma.
"
01/01/1994 - "
These observations clearly indicate that LISA 1-6 and CAM 123-6 constitute a part of KL-6, but that they are superior to KL-6 as tumor markers for pancreatic cancer and for pulmonary adenocarcinoma respectively, because of their much lower false-positive rates.
"
4.
Lung Neoplasms (Lung Cancer)
01/01/1997 - "
In differentiating pulmonary adenocarcinoma from other lung cancer, the diagnostic accuracy of CAM 123-6 was 81% and that of CEA was 74%, although there was no significant difference between them.
"
01/01/1997 - "
For discriminating lung cancer from benign lung disease, the combination of CAM 123-6, SCC, and NSE showed 64% diagnostic accuracy, and the combination of CEA, SCC, and NSE 65%.
"
Related Drugs and Biologics
1.
Tumor Biomarkers (Tumor Markers)
2.
Carcinoembryonic Antigen
3.
Biomarkers (Surrogate Marker)
4.
Phosphopyruvate Hydratase (Enolase)
5.
Mucins
6.
Horseradish Peroxidase
7.
squamous cell carcinoma-related antigen