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MDL 100173

(S)-isomer is MDL 100173; (R)-isomer is MDL 101628; RN refers to (4S-(4alpha,7alpha(R*),12bbeta)-isomer; structure given in first source

Also Known As:

MDL 100,173; MDL 101,628; MDL 101628; MDL-100,173; MDL-100173; MDL-101,628; MDL-101628

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - MDL 100173: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzazepines: 5
      - MDL 100173: 1

Related Diseases

1.

Hypertension (High Blood Pressure)

07/01/1995 - "Urinary excretion of atrial natriuretic peptide (ANP) was increased by MDL 100,173 treatment in all three models of hypertension. "
07/01/1995 - "In this study, we compared the activities of MDL 100,173, a novel subnanomolar inhibitor of both ACE and NEP, with those of equimolar doses of captopril, a selective ACE inhibitor, following intravenous administration in these three rat models of hypertension. "

Related Drugs and Biologics

1.	Captopril (Capoten)
2.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
3.	Atrial Natriuretic Factor (ANF)

Related Therapies and Procedures

1.	Intravenous Administration