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1- (1,3- benzodioxol- 5- ylcarbonyl)piperidine

crosses the blood brain barrier & enhances synaptic responses in freely moving animals

Also Known As:

1,3-BYCP; 1-BCP; BA 14; BA-14

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - 1-(1,3-benzodioxol-5-ylcarbonyl)piperidine: 2
  - Dioxoles
    - 1-(1,3-benzodioxol-5-ylcarbonyl)piperidine: 2

Experts

1.	Fan, Wutu: 1 article (01/2014)
2.	Li, Chenrui: 1 article (01/2014)
3.	Mei, Qibing: 1 article (01/2014)
4.	Niu, Yinbo: 1 article (01/2014)
5.	Pan, Yalei: 1 article (01/2014)
6.	Wu, Xianglong: 1 article (01/2014)
7.	Zhai, Yuankun: 1 article (01/2014)
8.	Falcão-Pires, Inês: 1 article (09/2011)
9.	Gonçalves, Nádia: 1 article (09/2011)
10.	Leite-Moreira, Adelino F: 1 article (09/2011)

Related Diseases

1.	Fatigue 01/01/2014 - "Therefore, this study demonstrated for the first time that the supplementation of 1-BCP, as a positive allosteric modulator of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor, could enhance the endurance capacity of mice and facilitated them recovery from fatigue. "
2.	Fibrosis (Cirrhosis) 09/01/2011 - "At the extracellular matrix level, fibrosis (BA 10.8 ± 0.9%, SHAM 5.3 ± 0.6%), pro-MMP-2 and MMP-9 activities increased and, in vivo, relaxation was impaired (τ; BA 14.0 ± 0.9 ms, SHAM 12.9 ± 0.4 ms). "
3.	Body Weight (Weight, Body) 01/01/2014 - "Mice were given either vehicle or 1-BCP (0.1, or 0.2 mmol/kg body weight daily) by intraperitoneal injection once daily for 2 weeks. "

Related Drugs and Biologics

1.	AMPA Receptors (AMPA Receptor)
2.	propionic acid (potassium propionate)
3.	progelatinase
4.	salicylhydroxamic acid (SHAM)

Related Therapies and Procedures

1.	Intraperitoneal Injections