A-1 antigen

marker for experimental peripheral nerve injury; recognized by monoclonal antibody BIKS; abundant in all tissue macrophages & in small amounts in normal Schwann cells

Also Known As:

cytoplasmic vesicle-associated molecule 1; membrane-associated intracytoplasmic antigen 1

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - A-1 antigen: 2

Related Diseases

1.	Peripheral Nerve Injuries 11/15/1993 - "The A-1 antigen: a novel marker in experimental peripheral nerve injury."
2.	Wallerian Degeneration 11/15/1993 - "Following axotomy, the A-1 antigen appears to be translocated from a perinuclear site to accumulate in large quantities around myelin ovoids in Schwann cells, as well at the nodes of Ranvier-sites where Wallerian degeneration is known to commence. "
3.	Herpes Zoster 03/01/1994 - "On the other hand, neither A23187 nor the zona solution affected the immunoreactivity or the fluorescence intensity of caput epididymal sperm, while the A-1 antigen was present in both the immature sperm from the caput epididymis of adult mice and in the mature sperm from the cauda epididymis of the same mice.(ABSTRACT TRUNCATED AT 250 WORDS)"
4.	Crush Injuries 11/15/1993 - "During repair of crush injury, however, the level of antigen drops concomitant with the ingrowth of regenerating axons, suggesting axonal control of A-1 antigen expression."

Related Drugs and Biologics

1.	Solutions
2.	Antigens
3.	Calcimycin (A23187)

Related Therapies and Procedures

1.	Axotomy