P-selectin ligand protein

RefSeq NM_009151 (mouse); NM_001013230 (rat); NM_003006 (human)

Also Known As:

CD162 antigen; CD162 antigen, mouse; CD162 protein, human; CD162 protein, mouse; MTH Ag, mouse; P-selectin glycoprotein ligand-1; PSGL-1 protein, human; Psgl-1 protein, mouse; Psgl1 protein, mouse; Psgl1 protein, rat; SELPLG protein, human; Selpl protein, mouse; Selpl protein, rat; metastatic T-cell hybridoma antigen, mouse; selectin P ligand protein, human; selectin, platelet (p-selectin) ligand, mouse; selectin, platelet (p-selectin) ligand, rat

Networked: 131 relevant articles (5 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Eitzman, Daniel T: 4 articles (01/2018 - 01/2012)
2.	Guo, Chiao: 4 articles (01/2018 - 01/2012)
3.	Wang, Hui: 4 articles (01/2018 - 01/2012)
4.	Constantin, Gabriela: 4 articles (12/2013 - 06/2003)
5.	Piccio, Laura: 4 articles (12/2013 - 06/2003)
6.	Rossi, Barbara: 4 articles (12/2013 - 06/2003)
7.	Scarpini, Elio: 4 articles (12/2013 - 06/2003)
8.	McEver, Rodger P: 4 articles (08/2012 - 06/2003)
9.	Sato, Shinichi: 4 articles (11/2011 - 05/2003)
10.	Yanaba, Koichi: 4 articles (11/2011 - 05/2003)

Related Diseases

1.	Atherosclerosis 01/01/2018 - "The metabonomics study of P-selectin glycoprotein ligand-1 (PSGL-1) deficiency inhibiting the progression of atherosclerosis in LDLR-/- mice." 01/01/2018 - "AS an inflammatory molecule, p-selectin glycoprotein ligand-1 (PSGL-1) played an important role in the inflammatory process of atherogenesis involving the recruitment of leukocyte and transmitting signals to activate leukocyte during the adhesion process. " 06/24/2008 - "P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice." 11/01/2021 - "Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis." 11/01/2007 - "Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study."
2.	Vascular System Injuries 05/07/2002 - "Recent studies suggest that prevention of platelet-leukocyte binding via P-selectin glycoprotein ligand-1 (PSGL-1) may be beneficial in animal models of vascular injury. " 12/01/2006 - "At sites of vascular injury, P-selectin exposure by activated endothelial cells or platelets leads to the rapid recruitment of MPs bearing the P-selectin glycoprotein ligand-1 and blood-borne TF, thereby triggering coagulation. " 01/01/2018 - "Recently, in a mice model, tumor cell-derived EVs were shown to deliver coagulant TF to activated platelets at a site of vascular injury via interaction between P-selectin glycoprotein ligand-1 (PSGL-1) and P-selectin. "
3.	Obesity 12/01/2012 - "We tested the hypothesis that deficiency of P-selectin glycoprotein ligand-1 (Psgl-1) would improve the endothelial dysfunction associated with obesity. " 12/01/2012 - "Obesity-induced endothelial dysfunction is prevented by deficiency of P-selectin glycoprotein ligand-1." 01/01/2011 - "P-selectin glycoprotein ligand-1 deficiency is protective against obesity-related insulin resistance."
4.	Mesenteric Ischemia 09/01/1999 - "Acute mesenteric ischemia and reperfusion: protective effects of recombinant soluble P-selectin glycoprotein ligand-1."
5.	Stroke (Strokes) 04/01/2023 - "In thromboembolic stroke rats, QSYQ significantly attenuated infarct area, improved neurological recovery, reduced PLA formation, and inhibited P-selection (CD62P)/ P-selectin glycoprotein ligand-1 (PSGL-1) expressions. "

Related Drugs and Biologics

1.	Apolipoproteins
2.	Cytokines
3.	P-Selectin
4.	Ligands
5.	E-Selectin
6.	L-Selectin
7.	Scavenger Receptors (Scavenger Receptor)
8.	Chemokines
9.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
10.	CD40 Ligand (CD40L)

Related Therapies and Procedures

1.	Immunotherapy
2.	Liver Transplantation