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NF-kappa B kinase

activates DNA-binding activity of NFkB by directly phosphorylating its p65 & p50 subunits; does not phosphorylate IkB; may have a central role in mediating various signals to NFkB; MW 43 kDa; amino acid sequence in second source; RefSeq NM_003954 (human), NM_016896 (mouse)
Also Known As:
MAP3K14 protein, human; Map3k14 protein, mouse; Map4k4 protein, mouse; NF- kappa beta-inducing kinase, human; NF-kappaB-inducing kinase; NFkB kinase; NIK protein, human; Nik protein; Nik protein, mouse; mitogen-activated protein kinase kinase kinase 14, human; mitogen-activated protein kinase kinase kinase 14, mouse; nuclear factor kappa B kinase
Networked: 35 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Schmidt-Supprian, Marc: 2 articles (11/2014 - 08/2008)
2. Yamaguchi, Noritaka: 2 articles (10/2009 - 09/2009)
3. Inoue, Jun-ichiro: 2 articles (10/2009 - 09/2009)
4. Semba, Kentaro: 2 articles (10/2009 - 09/2009)
5. Richmond, Ann: 2 articles (05/2008 - 01/2004)
6. Dhawan, Punita: 2 articles (05/2008 - 01/2004)
7. Liu, Qing-hui: 1 article (07/2015)
8. Liu, Peng-fei: 1 article (07/2015)
9. Huang, Jie: 1 article (07/2015)
10. Wu, Yin: 1 article (07/2015)

Related Diseases

1. Necrosis
2. Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
3. Inflammation
4. Infection
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. NF-kappa B (NF-kB)
2. I-kappa B Kinase
3. Viral Regulatory and Accessory Proteins
4. Phosphotransferases (Kinase)
5. NF-kappaB inhibitor alpha
6. TNF Receptor-Associated Factor 2 (TRAF2)
7. Proteins (Proteins, Gene)
8. Insulin (Novolin)
9. Immunoglobulin E (IgE)
10. NF-kappa B kinase