3-hydroxy-5-estrane-17-carbonitrile (ACN)

02/01/2017 - "In this study, we aimed to determine whether ACN and their metabolites from plasma (PAM), isolated from blood of healthy volunteers after ingestion of an ACN-rich juice, are effective in modulating cancer cell migration in vitro. "
01/01/2021 - "Test characteristics for each FIT for advanced colorectal neoplasia (ACN) will be calculated using colonoscopy as the gold standard. "
09/01/2023 - "This study aims to devise and validate a scoring system based on metabolic parameters to predict the risk of advanced colorectal neoplasia (ACN) in a large Chinese population. "
08/01/2021 - "This study aimed to elucidate the incidence of metachronous neoplasia during post-polypectomy surveillance in individuals with ACN at baseline and examine the risk factors for its high incidence. "
05/21/2021 - "The aim of our study was to compare model performance of binary logistic regression (BLR), polytomous logistic regression (PLR), and classification and regression tree (CART) between the clinical prediction scores of advanced colorectal neoplasia (ACN) in asymptomatic Thai patients.We"

10/01/2019 - "In this study, we used AP (117, 234 and 351 mg·kg-1) pretreatment intragastrically to resist the neurotoxicity caused by ACN gavage (46 mg·kg-1) for 28 days, and then detected the oxidative stress, inflammation mediated by the TLR4/NF-κB signaling pathway, and apoptosis to evaluate the protective effect of AP. "
10/01/2019 - "Current studies have found that the neurotoxicity is mainly related to oxidative damage and inflammation induced by ACN. "
08/01/2018 - "Therefore, the present study aimed to evaluate the role of AP on ACN-induced inflammation and apoptosis in germ cells and whether it is through the NF-κB signaling pathway. "
07/01/2019 - "In addition, PA induces inflammation with activation of NF-κB pathway, whereas ACN extract pretreatment dose-dependently inhibited this pathway. "
11/01/2017 - "In conclusion, AP reduces ACN-induced decreasing sperm quality by inhibition of inflammation and oxidative stress."

12/01/2014 - "We report a case of ACN with soft tissue hypertrophy and deep venous malformation (possibly a variant of Klippel-Trenaunay) in a 4-year-old male child. "
03/09/2021 - "The present study investigated the ability of anthocyanin (ACN) and non-anthocyanin polyphenol (PP) fractions from lingonberry fruit to mitigate adipose tissue hypertrophy and endothelial dysfunction using 3T3-L1 adipocytes and human umbilical vein endothelial cells (HUVECs). "
07/01/2019 - "Herein, we evaluated the in vitro protective effects of an ACN rich extract against palmitic acid (PA)-induced hypertrophy, inflammation, and insulin resistance in 3T3-L1 adipocytes. "

12/01/2006 - "This study looked at ascertaining the efficacy of Advanced Clinical Nurses' (ACN) suturing dermal lacerations in tertiary, regional and rural ED settings. "
12/01/2006 - "Eighty patients requiring sutures for dermal lacerations that were repaired by an ACN. "

10/25/2022 - "These results encourage a larger scale in vivo study to confirm that ACN may help to fight BC invasion and metastasis."
10/25/2022 - "ACN also lowered Cenpf mRNA in lungs, associated with lung metastasis lesions and poor survival. "