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febuxostat

structure given in first source; unlike allopurinol, febuxostat is not reincorporated into nucleotides in purine metabolic pathways and does not affect pyrimidine metabolism
Also Known As:
2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid; TEI 6720; TEI-6720; Uloric; 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-
Networked: 206 relevant articles (37 outcomes, 61 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. MacDonald, Patricia A: 10 articles (11/2013 - 03/2005)
2. Hosoya, Tatsuo: 9 articles (09/2015 - 06/2011)
3. Becker, Michael A: 8 articles (02/2012 - 03/2005)
4. Schumacher, H Ralph: 8 articles (02/2010 - 03/2005)
5. Yamamoto, Tetsuya: 7 articles (09/2015 - 06/2011)
6. Ueda, Takanori: 7 articles (09/2015 - 06/2011)
7. Hunt, Barbara: 7 articles (07/2012 - 11/2008)
8. Zhao, Lin: 7 articles (01/2011 - 03/2005)
9. Shiozawa, Aki: 6 articles (12/2015 - 03/2014)
10. Fujimori, Shin: 6 articles (09/2015 - 06/2011)

Related Diseases

1. Gout
2. Hyperuricemia
3. Renal Insufficiency (Renal Failure)
4. Hematologic Neoplasms (Hematological Malignancy)
5. Reperfusion Injury

Related Drugs and Biologics

1. Allopurinol (Remid)
2. Uric Acid (Urate)
3. Xanthine Oxidase
4. purine
5. rasburicase (Elitek)
6. benzbromarone drug combination allopurinol
7. polyethylene glycol-uricase
8. Xanthine Dehydrogenase
9. Benzbromarone
10. Xanthine

Related Therapies and Procedures

1. Renal Dialysis (Hemodialysis)
2. Transplantation (Transplant Recipients)
3. Ligation
4. Drug Therapy (Chemotherapy)
5. Investigational Therapies (Experimental Therapy)