metomidate

was heading 1975-94 (see under IMIDAZOLES 1975-90); METHOXIMOL was see METOMIDATE 1975-94; use IMIDAZOLES to search METOMIDATE 1975-94; a hypnotic and sedative that may also function as an anesthetic; now banned as an anesthetic for swine; C11-metomidate used as tracer for PET for adrenal neoplasms

Also Known As:

Networked: 50 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Sundin, Anders: 6 articles (01/2021 - 03/2003)
2.	Sundin, A: 4 articles (12/2011 - 02/2000)
3.	Gomez-Sanchez, Celso E: 3 articles (01/2022 - 12/2020)
4.	Hellman, Per: 3 articles (01/2021 - 04/2006)
5.	Seppänen, Marko: 3 articles (01/2021 - 02/2013)
6.	Gurnell, Mark: 3 articles (01/2019 - 06/2015)
7.	Powlson, Andrew S: 3 articles (01/2019 - 06/2015)
8.	Reilhac, Anthonin: 2 articles (01/2022 - 08/2021)
9.	Antoni, Gunnar: 2 articles (01/2021 - 08/2014)
10.	Arola, Johanna: 2 articles (01/2021 - 12/2020)

Related Diseases

1.	Hypertension (High Blood Pressure) 01/01/2023 - "The primary objective of our prospective study of 143 patients with PA ( NCT02945904 ) was to compare the accuracy of a non-invasive test, [11C]metomidate positron emission tomography computed tomography (MTO) scanning, with adrenal vein sampling (AVS) in predicting the biochemical remission of PA and the resolution of hypertension after surgery. " 01/01/2019 - "11 C-Metomidate PET/CT in conjunction with adrenal CT and AVS provided useful information which aided clinical decision-making for PA within a multidisciplinary hypertension clinic."
2.	Hyperaldosteronism (Conn Syndrome) 10/01/2023 - "[11C-metomidate PET-CT vs. selective adrenal vein sampling for prediction of surgical success in primary aldosteronism : Results of the prospective MATCH study]." 01/01/2023 - "Parametric mapping for 11 C-metomidate PET-computed tomography imaging in the study of primary aldosteronism: Retraction." 01/01/2023 - "[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial." 01/01/2021 - "Parametric mapping for 11C-metomidate PET-computed tomography imaging in the study of primary aldosteronism." 12/01/2020 - "A total of 12 studies were included in the systematic review, which altogether addressed the use of 11C-metomidate in adrenal masses and the application of this tracer in primary aldosteronism. "
3.	Neoplasms (Cancer) 01/01/2016 - "11C-metomidate PET/CT can differentiate adrenocortical from nonadrenocortical tumors and a suspected ACC may be characterized and staged before surgery. " 04/01/2006 - "[11C]metomidate positron emission tomography of adrenocortical tumors in correlation with histopathological findings." 11/01/2000 - "PET imaging of adrenal cortical tumors with the 11beta-hydroxylase tracer 11C-metomidate." 02/01/2000 - "PET imaging of adrenal cortical tumors with the 11beta-hydroxylase tracer 11C-metomidate." 11/01/1999 - "PET with [11C]-Metomidate for the Visualization of Adrenocortical Tumors and Discrimination from Other Lesions."
4.	Adenoma (Adenomas) 01/01/2021 - "Our work demonstrates that parametric Ki(VOX) was able to successfully differentiate between patients with bilateral hyperplasia and patients with unilateral adrenal adenoma in our cohort and that Ki may be considered be an additional useful metric to SUV in 11C-metomidate PET-CT imaging." 01/01/2016 - "11C-metomidate PET/CT is currently also used to help diagnose Conn's adenomas in primary aldosteronism, but further development is needed. " 01/01/2022 - "We curated an anonymized dataset of diagnostic 11C-metomidate PET/CT images of 14 patients with aldosterone producing adenomas (APA). " 01/01/2017 - "11C-metomidate PET-CT scanning can identify aldosterone-producing adenomas after unsuccessful lateralisation with CT/MRI and adrenal venous sampling." 01/01/2019 - "To describe clinical practice experience of 11 C-Metomidate PET/CT as an adjunct to adrenal vein sampling (AVS) in the lateralization of aldosterone-producing adenomas (APA) in primary aldosteronism (PA). "
5.	Adrenocortical Carcinoma 01/01/2023 - "[11C]Metomidate positron emission tomography (PET) is currently used for staging of adrenocortical carcinoma and for lateralization in primary aldosteronism (PA). " 09/01/2007 - "The 11b-hydroxylase inhibitor, metomidate labeled with 11C has been used to scintigraphically identify tissues of adrenocortical origin, to accurately identify recurrent and metastatic adrenocortical carcinoma and may be useful in assessing the malignant potential of these tumors and predicting survival in afflicted patients. " 11/18/2016 - "Particular consideration is given to iodo-metomidate PET tracers for the diagnosis and management of adrenocortical carcinoma, and the increasingly recognized utility of 11C-metomidate PET-CT in primary aldosteronism."

Related Drugs and Biologics

1.	Azaperone
2.	Aldosterone
3.	metomidate
4.	Radiopharmaceuticals
5.	5-Hydroxytryptophan (5 Hydroxytryptophan)
6.	Hydrocortisone (Cortisol)
7.	Etomidate
8.	Enzymes
9.	Dihydroxyphenylalanine (Dopa)
10.	Dexamethasone (Maxidex)

Related Therapies and Procedures

1.	Catheters
2.	Anesthesia
3.	Analgesia
4.	Adrenalectomy