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4-amino-3-S-glutathionylphenol
nephrotoxic metabolite of 4-aminophenol
Also Known As:
4-AGTP
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Oligopeptides: 519
Glutathione: 14524
4-amino-3-S-glutathionylphenol: 1
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Phenols: 677
4-amino-3-S-glutathionylphenol: 1
Related Diseases
1.
Necrosis
11/01/1991 - "
4-Amino-3-S-glutathionylphenol produced a dose-dependent (92-920 mumol kg-1) necrosis of the proximal tubular epithelium and altered renal excretory function.
"
11/01/1991 - "
The renal necrosis produced by 4-amino-3-S-glutathionylphenol was very similar to that produced by PAP (367-920 mumol kg-1), both functionally and histologically, except that smaller doses of the glutathione conjugate were required.
"
Related Drugs and Biologics
1.
Glutathione (Reduced Glutathione)