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MAP-kinase-activated kinase 2

a protein kinase which is activated by mitogen-activated protein kinase; phosphorylates tyrosine hydroxylase on serine residues 19 and 40 and activates it; substrate specificity is similar to checkpoint kinase 1 & 2; do not confuse with HSP25, also known as heat-shock protein 25
Also Known As:
HSP 27 kinase; HSP25 kinase; MAP kinase-activated protein kinase 2, mouse; MAP kinase-activated protein kinase-2, human; MAP-kinase-activated protein kinase 2; MAPKAP kinase 2; MAPKAP kinase 2 protein, mouse; MAPKAP kinase-2; MAPKAP kinase-2 protein, human; MAPKAPK-2; MAPKAPK2; MAPKAPK2 protein, human; MK2 protein, human; MK2 protein, mouse; Mapkapk2 protein, mouse; heat shock protein 27 kinase; heat-shock protein 27 kinase; hsp27 kinase; mitogen-activated protein kinase-activated protein kinase 2, human; mitogen-activated protein kinase-activated protein kinase 2, mouse
Networked: 63 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Gaestel, Matthias: 5 articles (01/2015 - 11/2007)
2. Davis, Terence: 2 articles (01/2015 - 01/2013)
3. Bagley, Mark C: 2 articles (01/2015 - 01/2013)
4. Kipling, David: 2 articles (01/2015 - 01/2013)
5. Lander, Cynthia: 2 articles (12/2014 - 07/2013)
6. Birner, Peter: 2 articles (12/2014 - 04/2012)
7. Schoppmann, Sebastian F: 2 articles (12/2014 - 04/2012)
8. Lu, Jiachun: 2 articles (01/2014 - 08/2012)
9. Zhou, Yifeng: 2 articles (01/2014 - 08/2012)
10. Li, Yinyan: 2 articles (01/2014 - 08/2012)

Related Diseases

1. Ischemia
2. Werner Syndrome (Werner's Syndrome)
3. Lung Neoplasms (Lung Cancer)
4. Prostatic Neoplasms (Prostate Cancer)
5. Pancreatitis

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Heat-Shock Proteins (Heat-Shock Protein)
3. SB 203580
4. Protein-Tyrosine Kinases (Tyrosine Kinase)
5. Transforming Growth Factor beta (TGF-beta)
6. Phospholipase D
7. 2-chloroquinoline
8. p38 Mitogen-Activated Protein Kinases
9. Protein Kinases (Protein Kinase)
10. MAP-kinase-activated kinase 3

Related Therapies and Procedures

1. Ischemic Postconditioning
2. Aftercare (After-Treatment)