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phenylalanyl- leucyl- leucyl- arginyl- asparagine

a pentapeptide; an inhibitor of TRP-mediated platelet aggregation

Also Known As:

FLLRN; H 8325; H-8325; Phe-Leu-Leu-Arg-Asn

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - phenylalanyl-leucyl-leucyl-arginyl-asparagine: 2

Related Diseases

1.	Neoplasms (Cancer) 02/01/1995 - "Finally, peptides TRP 14 and TRP 7 (SFLLRNP), but not TRP 5 (FLLRN), were found to mimic alpha-thrombin in stimulating tumor cell adhesion to fibronectin, suggesting that the thrombin receptors expressed on solid tumor cells are biologically functional."
2.	Blister (Bulla) 03/15/1996 - "We report that these cells, when exposed to thrombin or SFLLRN (the peptide Ser-Phe-Leu-Leu-Arg-Asn, a thrombin-receptor ligand) rapidly change shape, forming membrane 'blebs', detectable by differential interference contrast or confocal microscopy, as well as labelled 3-phosphorylated phosphoinositides. "

Related Drugs and Biologics

1.	Thrombin Receptors (Thrombin Receptor)
2.	Thrombin
3.	Peptides (Polypeptides)
4.	Phosphatidylinositols (Phosphatidylinositol)
5.	Ligands
6.	Fibronectins (Fibronectin)
7.	thrombin receptor peptide SFLLRNP
8.	thrombin receptor peptide (42-47)