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BMS 188107
structure given in first source
Also Known As:
BMS-188107; 5H-Pyrano(3,2-c)quinolin-5-one, 2,3,4,6-tetrahydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-(phenylmethyl)-, trans-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinolines: 146
Quinolones: 2938
BMS 188107: 1
Related Diseases
1.
Reperfusion Injury
10/01/1993 - "
Significant improvements in postischemic contractile function and reductions in lactate dehydrogenase release were observed with 1 to 10 microM BMS-188107, indicating significant reductions in ischemic/reperfusion injury.
"
2.
Ischemia
10/01/1993 - "
Pretreatment (before ischemia) with BMS-188107 caused significant cardiodepressant activity and increased coronary flow only at a concentration of 10 microM, although modest negative inotropic effects were observed at the 0.5 and 1 microM concentrations.
"
10/01/1993 - "
BMS-188107 was given before ischemia at 0.5 to 10 microM.
"
Related Drugs and Biologics
1.
L-Lactate Dehydrogenase (Lactate Dehydrogenase)