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BMY 21190
structure given in first source
Also Known As:
BMY-21190; BMY21190
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
BMY 21190: 2
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinolines: 146
BMY 21190: 2
Related Diseases
1.
Infarction (Infarctions)
01/01/1995 - "
It is suggested that BMY21190 reduces infarct size through the inhibition of neutrophil infiltration in the canine model.
"
01/01/1995 - "
The infarct zone/area at risk of the BMY21190 group was significantly smaller than that of the vehicle group (36.1 +/- 7.8%; 62.4 +/- 4.3%, respectively; p < 0.05).
"
01/01/1995 - "
This study was performed to assess the effect of BMY21190, an inhibitor of cAMP phosphodiesterase, on infarct size using a canine ischemic model that underwent a 90-min occlusion and a 6-hour reperfusion of the left coronary artery.
"
01/01/1995 - "
Effects of BMY21190, an inhibitor of cAMP phosphodiesterase, on infarct size and myeloperoxidase activity in the ischemic myocardium of a canine occlusion-reperfusion model.
"
2.
Thrombosis (Thrombus)
10/01/1993 - "
BMY21190 treatment reduced the development of the LCX thrombus mass, as compared to that in the controls.
"
10/01/1993 - "
BMY21190 was evaluated for its ability to modify the development of experimental thrombosis resulting from anodal current injury (100 microA for 6 h) of the intimal surface of the left circumflex coronary artery (LCX) in anesthetized dogs.
"
10/01/1993 - "
Antithrombotic effects of BMY21190, an inhibitor of cAMP phosphodiesterase, in a canine model of coronary artery thrombosis.
"
Related Drugs and Biologics
1.
3',5'-Cyclic-AMP Phosphodiesterases (3',5' Cyclic Nucleotide Phosphodiesterase)
2.
Peroxidase (Myeloperoxidase)