HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

alpha-guaiaconic acid (GR 12)

inhibits arachidonic acid metabolism and modulates tumor angiogenesis; structure given in first source

Also Known As:

GR 12; 3,4-dimethyl-2,5-bis(4-hydroxy-3-methoxyphenyl)furan; GR-12

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - alpha-guaiaconic acid: 5
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        alpha-guaiaconic acid: 5

Experts

1.	Fleming,: 1 article (02/2001)
2.	Lum,: 1 article (02/2001)
3.	Roy,: 1 article (02/2001)
4.	Spragge,: 1 article (02/2001)

Related Diseases

1.	Tics (Tic) 12/20/1986 - "The hundred and ninety-two combinations were tested against 17 strains chosen from the results of MIC determination (disc method): 5 enterococci exhibiting low level resistance (r) or high level resistance (R) to streptomycin (S) and gentamicin (G): 2 strains Sr Gr, 2 strains SR Gr and 1 strain Sr GR; 12 enterobacteria chosen for their resistance phenotypes to beta-lactams and aminoglycosides and because they are the most frequent clinical isolates: 2 strains Amos Tics Ctns (group 1), 4 strains AmoR Tics CtnR (gr. "
2.	Stress Fractures (Stress Fracture) 02/01/2001 - "Furthermore, as the applied potential became more cathodic, Ti Gr-12 showed reduced ductility in terms of percent reduction in area and true fracture stress (sigma(f)). "
3.	Pyelonephritis 05/01/1987 - "The Escherichia coli pyelonephritis isolate GR-12, serotype O75K5, expressing adhesins specific for globoseries glycolipids (P fimbriae) and for mannosides (type-1 fimbriae), and its derivatives deficient in these factors were used, either singly or in combination, to establish experimental infections. "
4.	Infections 05/01/1987 - "The Escherichia coli pyelonephritis isolate GR-12, serotype O75K5, expressing adhesins specific for globoseries glycolipids (P fimbriae) and for mannosides (type-1 fimbriae), and its derivatives deficient in these factors were used, either singly or in combination, to establish experimental infections. "
5.	Esophageal Neoplasms (Esophageal Cancer) 10/21/1993 - "Enhanced tube formation of HOME cells by co-cultured esophageal cancer cells was almost completely inhibited by co-administration of GR-12 or GS-01. "

Related Drugs and Biologics

1.	beta-Lactams
2.	Streptomycin (Streptomycin Sulfate)
3.	Omeprazole (Prilosec)
4.	Mannosides
5.	Glycolipids
6.	Gentamicins (Gentamicin)
7.	Amoxicillin (Wymox)
8.	Aminoglycosides
9.	2- (N,N- dimethylamino)ethyl- 4- ethoxybenzoate (GS 01)