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tripeptidyl-peptidase 1

releases N-terminal tripeptides from polypeptides; involved in the degradation of bone collagen; mutations in gene are associated with the Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL); RefSeq NM_000391 (human); NM_009906 (mouse); NM_031357 (rat)
Also Known As:
CLN2 protein, human; Cln2 protein, mouse; Cln2 protein, rat; TPP-I protein, human; TPP1 protein, human; Tpp1 protein, mouse; Tpp1 protein, rat; ceroid-lipofuscinosis, neuronal 2 protein, human; ceroid-lipofuscinosis, neuronal 2 protein, mouse; ceroid-lipofuscinosis, neuronal 2 protein, rat; ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) protein, human; tripeptidyl aminopeptidase I; tripeptidyl aminopeptidase, human; tripeptidyl peptidase 1, mouse; tripeptidyl peptidase I; tripeptidyl peptidase I, mouse; tripeptidyl peptidase I, rat; tripeptidyl protease I; tripeptidyl-peptidase I; tripeptidyl-peptidase I, human
Networked: 60 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lobel, Peter: 13 articles (03/2014 - 10/2004)
2. Sleat, David E: 10 articles (03/2014 - 10/2004)
3. Sohar, Istvan: 9 articles (03/2014 - 05/2002)
4. Davidson, Beverly L: 5 articles (11/2015 - 10/2004)
5. Crystal, Ronald G: 5 articles (10/2012 - 12/2005)
6. Sondhi, Dolan: 5 articles (10/2012 - 12/2005)
7. Hackett, Neil R: 5 articles (10/2012 - 12/2005)
8. Kim, Kwi-Hye: 4 articles (03/2009 - 10/2004)
9. Passini, Marco A: 4 articles (04/2008 - 10/2004)
10. Lin, L: 4 articles (08/2001 - 07/2000)

Related Diseases

1. Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
2. Rheumatoid Arthritis
3. Neurodegenerative Diseases (Neurodegenerative Disease)
4. Lysosomal Storage Diseases (Lysosomal Storage Disease)
5. Nervous System Heredodegenerative Disorders

Related Drugs and Biologics

1. Serine Proteases (Serine Protease)
2. Cathepsin C
3. Cysteine Proteases (Cysteine Protease)
4. Lysergic Acid Diethylamide (LSD)
5. Glycoside Hydrolases (Endoglycosidases)
6. Collagen
7. Cathepsin D
8. Cathepsin B
9. Aspartic Acid (Aspartate)
10. dipeptidyl peptidase II

Related Therapies and Procedures

1. Therapeutics