Ro 46-2005

an orally active non-peptide antagonist of endothelin receptors; structure given in first source

Also Known As:

4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)-4-pyrimidinyl)benzenesulfonamide; Ro-46-2005; Ro46-2005

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neointima 05/01/1995 - "The histochemical experiments with biotinylated ET-1 at lysine-9 side chain alone or in combination with unlabeled ET-1, BQ123, Ro 46-2005, or IRL1620, showed the ETA receptors to be localized mainly in the media, whereas the ETB receptors localized mainly in the neointima. "

1.	cyclo(Trp-Asp-Pro-Val-Leu)