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SK&F 108922

synthetic HIV-1 protease inhibitor with antiviral activity; hydroxyethylene isostere of Phe-Ala

Also Known As:

Cbz-Ala-Phe(CH(OH)CH2)Ala-Val-valinol; SK&F-108922

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - SK&F 108922: 1

Related Diseases

1.

08/01/1993 - "In order to determine the potential for drug interaction effects on antiviral activity, an HIV-1 protease inhibitor (SK&F 108922) and AZT were studied in three different in vitro models of HIV-1 infection of T-cell lines, specifically, (1) acutely infected cells infected at low multiplicity, (2) HIV-1 chronically-infected cells and (3) co-cultivations of chronically infected with non-infected cells. "

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)
2.	Human immunodeficiency virus 1 p16 protease