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aggrecanase

cleaves aggrecan from articular cartilage predominantly between Glu-373 and Ala-374; activity found in bovine articular cartilage, bovine growth plate and chondrocyte monolayer cultures
Also Known As:
NITEGE
Networked: 90 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lohmander, L S: 5 articles (05/2012 - 02/2006)
2. Struglics, A: 4 articles (05/2012 - 02/2006)
3. Larsson, S: 4 articles (05/2012 - 02/2006)
4. Lohmander, L Stefan: 3 articles (12/2012 - 01/2009)
5. Struglics, André: 3 articles (12/2012 - 01/2009)
6. Arner, Elizabeth C: 3 articles (01/2008 - 02/2002)
7. Tortorella, Micky D: 3 articles (01/2008 - 02/2002)
8. Caterson, B: 3 articles (01/2008 - 08/2000)
9. Sandy, J D: 3 articles (07/2007 - 02/2000)
10. Pratta, M A: 3 articles (07/2006 - 06/2001)

Related Diseases

1. Osteoarthritis
2. Chondrosarcoma
3. Joint Diseases (Joint Disease)
4. Neoplasms (Cancer)
5. Squamous Cell Carcinoma (Epidermoid Carcinoma)

Related Drugs and Biologics

1. Aggrecans (Aggrecan)
2. Collagen
3. Tretinoin (Retinoic Acid)
4. Sepharose (Agarose)
5. Matrix Metalloproteinases
6. Thrombospondins
7. Proteoglycans (Proteoglycan)
8. Interleukin-1 (Interleukin 1)
9. Metalloproteases (Metalloproteinases)
10. Messenger RNA (mRNA)

Related Therapies and Procedures

1. Therapeutics
2. Intra-Articular Injections