|1.||Pasternack, Gary R: 4 articles (12/2007 - 01/2004)|
|2.||Brody, Jonathan R: 3 articles (01/2010 - 01/2004)|
|3.||Huyton, Trevor: 2 articles (05/2013 - 07/2007)|
|4.||Yeo, Charles J: 2 articles (01/2010 - 12/2007)|
|5.||Williams, Timothy K: 2 articles (01/2010 - 12/2007)|
|6.||Kadkol, Shrihari S: 2 articles (12/2007 - 01/2004)|
|7.||Fan, Z: 2 articles (09/2006 - 11/2001)|
|8.||Adegbola, Onikepe: 2 articles (08/2005 - 04/2005)|
|9.||Fan, Zusen: 2 articles (10/2003 - 04/2002)|
|10.||Lieberman, Judy: 2 articles (10/2003 - 04/2002)|
04/19/2001 - "This study focuses upon the role of pp32 in tumor suppression. "
07/16/1999 - "In this study, we identify the region of pp32 associated with the ability to inhibit oncogene-mediated transformation in a rat embryo fibroblast system, an in vitro correlate of tumor-suppressive activity. "
05/01/2013 - "The pp32 (ANP32A) gene acts as a tumor suppressor while its closely related homologue pp32r1 (ANP32C) is oncogenic and is overexpressed in breast, prostate and pancreatic tumors. "
03/13/2009 - "PHAPI/pp32 is a tumor suppressor whose expression is altered in various human cancers. "
01/01/2008 - "Conditional expression of pp32/PHAPI sensitized NSCLC cells to apoptosis in vitro and in a murine tumor model in vivo. "
|2.||Breast Neoplasms (Breast Cancer)
07/01/2001 - "These results suggest that alternative expression of pp32 family members may be common in human breast cancer and the analysis of the profile of pp32-related expression might be helpful in understanding the role of these genes in breast cancer pathogenesis."
11/01/2004 - "Coimmunoprecipitation experiments demonstrate that endogenously expressed pp32 and ER alpha from MCF-7 breast cancer cells interact. "
07/01/2001 - "The purpose of this pilot study was to determine pp32-related expression and whether alternative gene use among the pp32 family members occurred in human breast cancer. "
07/01/2001 - "Expression of pp32 gene family members in breast cancer."
12/01/2007 - "On the basis of this study and previous functional work that shows pp32 can inhibit K-ras transformation, we propose that reduction in pp32 expression levels may be a critical event in the progression of pancreatic tumorigenesis in an aggressive subset of pancreatic ductal adenocarcinomas."
02/15/1998 - "This study found elevated pp32 expression in 98% (54/55) of prostatic adenocarcinomas of Gleason score > or = 5 (P < 0.0001). "
04/19/2001 - "pp32r1 and pp32r2, the oncogenic members of the pp32 family, are expressed in prostatic adenocarcinoma, while adjacent benign prostate continues to express pp32. "
12/01/2007 - "In this study, we evaluated pp32 protein expression in relation to the differentiation status of pancreatic ductal adenocarcinomas and precursor lesions of the pancreatic cancers. "
12/01/2007 - "We validated pp32 expression by a second technique, immunoblot analysis of lysates from resected pancreatic ductal adenocarcinomas and pancreatic cancer cell lines. "
01/01/2004 - "We used anti-sense pp32 and RNAi transfection to study the effects of reduced pp32 expression in the TSU-Pr1 carcinoma cell line. "
07/01/2001 - "4/5 carcinomas continued to express pp32 but one was devoid of pp32 expression. "
07/01/2001 - "Oncogenic pp32r1 (5/5) and pp32r2 (3/5) expression was observed in carcinomas where as benign breast tissues expressed pp32. "
12/01/1996 - "pp32 overexpression induces nuclear pleomorphism in rat prostatic carcinoma cells."
03/01/1999 - "Because pp32 inhibits oncogene-mediated transformation, we investigated its paradoxical expression in cancer by comparing the sequence and function of pp32 species from paired benign prostate tissue and adjacent prostatic carcinoma from three patients. "
|1.||Adenosine Triphosphatases (ATPase)
|2.||5- amino- 7- (2- phenylethyl)- 2- (2- furyl)pyrazolo(4,3- e)- 1,2,4- triazolo(1,5- c)pyrimidine
|3.||RNA-Directed DNA Polymerase (Reverse Transcriptase)
|5.||Proteins (Proteins, Gene)
|6.||Messenger RNA (mRNA)
|8.||NM23 Nucleoside Diphosphate Kinases
|10.||Interleukin-1beta (Interleukin 1 beta)
|1.||Drug Therapy (Chemotherapy)