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human platelet antigen 1b

epitope of platelet glycoprotein IIIa

Also Known As:

HPA-1b antigen, human; PI(A2) antigen, human; PLA2 antigen, human; Zw(b) antigen, human

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Isoantigens: 1221
    - Human Platelet Antigens: 286
      - human platelet antigen 1b: 6

Experts

1.	Scharf, R E: 2 articles (07/2005 - 03/2000)
2.	Zotz, R B: 2 articles (07/2005 - 03/2000)
3.	Coen Herak, Desiree: 1 article (01/2022)
4.	Gojčeta, Koraljka: 1 article (01/2022)
5.	Golubić Ćepulić, Branka: 1 article (01/2022)
6.	Grizelj, Ruža: 1 article (01/2022)
7.	Ostojić, Sanja Baršić: 1 article (01/2022)
8.	Tomac, Gordana: 1 article (01/2022)
9.	Gerhardt, Andrea: 1 article (01/2014)
10.	Howe, Nadja: 1 article (01/2014)

Related Diseases

1.	Myocardial Infarction 03/01/2000 - "Recently, we have demonstrated that human platelet antigen 1b (HPA-1b or P1A2) is a hereditary risk factor for platelet thrombogenicity leading to premature myocardial infarction in preexisting coronary artery disease. " 04/01/1998 - "Conflicting results of an association between the human platelet antigen 1b (HPA-1b or PlA2) allele and the risk of myocardial infarction and coronary artery disease have been reported. " 07/01/2005 - "Human platelet antigen 1b and alpha(2)807TT are associated with premature myocardial infarction but not with coronary artery disease, suggesting a role of distinct integrin genotypes for increased platelet thrombogenicity. " 07/01/2005 - "Conflicting results of an association of the human platelet antigen 1b (HPA-1b/PlA2), localized on the beta-subunit of the integrin alpha(IIb)beta3, and the alpha(2)807TT genotype of the integrin alpha2beta1 with coronary atherosclerosis and myocardial infarction have been reported. "
2.	Coronary Artery Disease (Coronary Atherosclerosis) 03/01/2000 - "Recently, we have demonstrated that human platelet antigen 1b (HPA-1b or P1A2) is a hereditary risk factor for platelet thrombogenicity leading to premature myocardial infarction in preexisting coronary artery disease. " 04/01/1998 - "Conflicting results of an association between the human platelet antigen 1b (HPA-1b or PlA2) allele and the risk of myocardial infarction and coronary artery disease have been reported. " 07/01/2005 - "Human platelet antigen 1b and alpha(2)807TT are associated with premature myocardial infarction but not with coronary artery disease, suggesting a role of distinct integrin genotypes for increased platelet thrombogenicity. " 07/01/2005 - "Conflicting results of an association of the human platelet antigen 1b (HPA-1b/PlA2), localized on the beta-subunit of the integrin alpha(IIb)beta3, and the alpha(2)807TT genotype of the integrin alpha2beta1 with coronary atherosclerosis and myocardial infarction have been reported. "
3.	Neonatal Alloimmune Thrombocytopenia 01/01/2022 - "Severe intracranial haemorrhage in neonatal alloimmune thrombocytopenia due to antibodies against human platelet antigen 1b: Case report and literature review."
4.	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/01/2014 - "Elevated lipoprotein(a) levels and homozygous human platelet antigen 1b (HPA-1b) genotype are risk factors for intrauterine growth restriction (IUGR)."
5.	Birth Weight (Birth Weights) 01/01/2014 - "A risk association could be shown for homozygous human platelet antigen 1b genotype (OR 3.2, P = 0.038) in women with a history for a newborn's birth weight below the 5th percentile. "

Related Drugs and Biologics

1.	Integrins
2.	Platelet Membrane Glycoprotein IIb
3.	Integrin alpha2beta1
4.	Lipoprotein(a)
5.	Antibodies