butolame
modified ESTRADIOL with amino-alcohol side chain at the C17 position; has anticoagulant & estrogenic effects; structure given in first source
Also Known As:
17 beta-(4'-hydroxy-1'-butylamino)-1,3,5(10)-estratriene-3-ol; 17 beta-(4-hydroxy-1-butylamino)-1,3,5(10)-estratrien-3-ol
Networked: 3
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Lordosis
01/01/2009
- " This work evaluates the influence of single and multiple administration of a homologous series of the AEs: prolame, butolame and pentolame on rat female sexual behavior to explore their capability of inducing lordosis by themselves. " 03/23/2009
- " Dose-response curves were performed in rats by single subcutaneous (s.c.) injection (timezero) of: E2 (approximately 0.3, 3, 30, 60, 300 microg/kg); EB (approximately 0.4, 4, 40, 80, 400 microg/kg); prolame, butolame, pentolame (approximately 40, 400, 2000 or 4000 mg/kg), vehicle (corn oil; 300 microL/day; approximately 1.2 mL/kg) as control; 24 h after, P (1 mg/rat in 100 microL of corn oil; approximately 4 to 5 mg/kg) was administered, and 5 to 7 h later LQ was evaluated (number of lordosis displays/number of mounts x 100). "
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2. | Uterine Cervical Neoplasms (Cancer of the Cervix)
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