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leukotriene D4 receptor (cysteinyl leukotriene receptor)

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma; stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung; this response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system; leukotriene D4 receptor was SY to SRS-A receptor (NM); use receptors, leukotriene (NM) to search through 1993; RefSeq NM_006639 (human)
Also Known As:
cysteinyl leukotriene receptor; CYSLTR1 protein, human; CysLT(1) receptor; CysLT1 receptor; HG55 protein, human; HMTMF81 protein, human; LTD4 receptor; cysteinyl leukotriene receptor 1 protein, human; receptor, leukotriene D4
Networked: 258 relevant articles (22 outcomes, 52 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wei, Er-Qing: 12 articles (01/2012 - 10/2002)
2. Zhang, Wei-Ping: 10 articles (01/2012 - 10/2002)
3. Fang, San-Hua: 7 articles (01/2012 - 11/2006)
4. Reiss, T F: 6 articles (07/2009 - 05/2000)
5. Kawano, Tetsuya: 5 articles (01/2014 - 05/2004)
6. Fukushima, Chizu: 5 articles (01/2014 - 05/2004)
7. Matsuse, Hiroto: 5 articles (01/2014 - 05/2004)
8. Kohno, Shigeru: 5 articles (01/2014 - 05/2004)
9. Peters-Golden, Marc: 5 articles (07/2008 - 01/2003)
10. Obase, Yasushi: 4 articles (01/2013 - 05/2004)

Related Diseases

1. Asthma (Bronchial Asthma)
2. Seasonal Allergic Rhinitis (Hay Fever)
3. Rhinitis
4. Hypersensitivity (Allergy)
5. Exercise-Induced Asthma (Asthma, Exercise Induced)

Related Drugs and Biologics

1. montelukast (Singulair)
2. zafirlukast (Accolate)
3. Leukotrienes
4. Leukotriene D4
5. pranlukast
6. Lipoxygenase Inhibitors
7. Loratadine (Alavert)
8. Cetirizine (Zyrtec)
9. Adrenal Cortex Hormones (Corticosteroids)
10. Messenger RNA (mRNA)

Related Therapies and Procedures

1. Ligation
2. Metered Dose Inhalers (Metered Dose Inhaler)
3. Therapeutics
4. Oral Administration