Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma; stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung; this response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system; leukotriene D4 receptor was SY to SRS-A receptor (NM); use receptors, leukotriene (NM) to search through 1993; RefSeq NM_006639 (human)
Also Known As:
cysteinyl leukotriene receptor; CYSLTR1 protein, human; CysLT(1) receptor; CysLT1 receptor; CysLT1R; HG55 protein, human; HMTMF81 protein, human; LTD4 receptor; cysteinyl leukotriene receptor 1 protein, human; receptor, leukotriene D4