Met-human growth hormone

has been sequenced; human growth hormone minus its signal sequence

Also Known As:

Met-hGH

Networked: 11 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Growth Hormone: 14884
        Met-human growth hormone: 11
  - Peptide Fragments: 373
    - Met-human growth hormone: 11
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Growth Hormone: 14884
        Met-human growth hormone: 11

Related Diseases

1.	Wounds and Injuries (Trauma) 03/01/1991 - "Since provision of met-hGH prevented protein catabolism in muscle and improved whole body nitrogen economy, investigations of the possible beneficial effects of met-hGH to prevent skeletal muscle vast after surgical trauma are advocated."
2.	Turner Syndrome (Turner's Syndrome) 08/01/1988 - "When growth velocity was expressed as standard deviation for age in girls with Turner syndrome, significant increases relative to the control group for year 1 (-0.1 SD) were seen in all three years of both combination therapy and met-hGH alone (combination, +6.6, +4.3, +3.0 SD; met-hGH, +3.1, +2.0, +1.4 SD). " 08/01/1988 - "Seventy girls with Turner syndrome, 4 to 12 years of age, participated in a prospective, randomized study to determine the effects on growth of methionyl human growth hormone (met-hGH) or oxandrolone. " 05/01/1986 - "Twenty patients with Turner's syndrome were treated with methionyl human growth hormone (met-hGH) produced by recombinant DNA technology. "
3.	Weight Gain 06/01/1988 - "Weight gain after 8 daily injections in the 5-dose long bone growth study indicated a rhGH potency of 0.80 (95% confidence interval, 0.5-1.23) relative to Met-hGH. "
4.	Acute-Phase Reaction 09/01/1984 - "Therefore, a phase I trial of met-hGH was carried out in healthy human adults; during the first trial, however, signs, symptoms, and clinical laboratory tests characteristic of an acute-phase response to pyrogenic agents was observed. "
5.	Pituitary Dwarfism 08/01/1986 - "Two children with pituitary dwarfism already developed in utero high antibody titres against Met-hGH but not against ECP. " 08/01/1983 - "Ten patients with idiopathic pituitary dwarfism were treated with methionyl human growth hormone (met-hGH) produced by recombinant DNA technology. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Nitrogen
3.	somatrem (Protropin)
4.	Oxandrolone (Anavar)
5.	Recombinant DNA (Recombinant DNA Research)
6.	Glutamine (L-Glutamine)
7.	Dipeptides
8.	salicylhydroxamic acid (SHAM)

Related Therapies and Procedures

1.	Injections
2.	Therapeutics