A 103 (A-103)

structure given in first source

Also Known As:

A-103; 2,3-(3-tetradecanoyloxytetradecanoyl)glucosamine-4-phosphate; 2,3-(C14-O-C14)glucosamine-4-phosphate; D-Glucose, 2-deoxy-2-((1-oxo-3-((1-oxotetradecyl)oxy)tetradecyl)amino)-, 4-(dihydrogen phosphate) 3-(3-((1-oxotetradecyl)oxy)tetradecanoate), (2(R),3(R))-

Networked: 34 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cesaretti, Jamie A: 2 articles (12/2009 - 08/2007)
2.	Stock, Richard G: 2 articles (12/2009 - 08/2007)
3.	Stone, Nelson N: 2 articles (12/2009 - 08/2007)
4.	Ahmed, Faruk: 1 article (03/2022)
5.	Akseer, Nadia: 1 article (03/2022)
6.	Ashorn, Ulla: 1 article (03/2022)
7.	Belizán, José: 1 article (03/2022)
8.	Bhutta, Zulfiqar Ahmed: 1 article (03/2022)
9.	Black, Robert E: 1 article (03/2022)
10.	Bétran, Ana Pilar: 1 article (03/2022)

Related Diseases

1.	Pathologic Constriction (Stenosis) 11/01/2006 - "This study was designed to assess the expression of smooth muscle actin (SMA) in the healing process after implanting a (103)Pd radioactive stent in the biliary duct, and to discuss the function and significance of this stent in preventing biliary stricture formation. "
2.	Body Weight (Weight, Body) 11/01/2021 - "A total of 70 male growing non-castrated pigs (Large White), with a 23.07 ± 2.87 kg average body weight (BW), were randomly allocated to three treatments in a 103 day trial: a CONTROL diet and two experimental diets, ALLIUM (5 g/kg of Allium spp. extract) and OLIVE (100 g/kg of olive pulp). "
3.	Fibrosarcoma 01/01/1996 - "A-703, A-607 and A-103 showed antitumor activity against Meth A fibrosarcoma in BALB/c mice. " 05/01/1995 - "A-607, A-608 and A-103 showed antitumor activity against Meth A fibrosarcoma in BALB/c mice, and furthermore, the enhancement of antitumor activity by a combination of A-608 with muramyl dipeptide (MDP) was observed.(ABSTRACT TRUNCATED AT 250 WORDS)" 11/01/1992 - "Meth A fibrosarcoma cells (5 x 10(5) were inoculated intradermally into BALB/c mice on day 0, and compound A-103 and/or GMDP was administered intravenously (i.v.) on days 7 and 9. Two i.v. injections of A-103 (50 micrograms) alone or GMDP (10 micrograms) alone induced 42.8 or 51.8% inhibition of the rate of tumor growth, however, A-103 (100 micrograms) with GMDP (10 micrograms) exhibited a high 68.7% inhibition rate 19 days after tumor inoculation. " 02/01/1992 - "The mitogenicity, lethal toxicity and antitumor activity against Meth A fibrosarcoma and the induction of tumor necrosis factor (TNF) of chemically synthesized compounds designated as A-103, 2,3-diacyloxyacylglucosamine-4-phosphate (GlcN-4-P), and A-503), heptose-(alpha 1----5)-2-keto-3-deoxyoctonic acid (KDO)-linked GlcN-4-P (A-103), were determined. " 11/01/1992 - "The combined effects of the synthetic glucosaminylmuramyl dipeptide (GMDP) on the antitumor activity of chemically synthesized lipid A analogs, compound A-103 (glucosamine-4-phosphate with (R)-3-tetradecanoyloxytetradecanoyl group at the C-2 and C-3 positions), Escherichia coli-type lipid A (506), Salmonella typhimurium LT-2 lipopolysaccharide (LPS) against Meth A fibrosarcoma in mice were examined. "
4.	Congenital Abnormalities (Deformity) 07/01/2015 - "Birth Defects Research (Part A) 103:597-602, 2015. " 07/01/2015 - "Birth Defects Research (Part A) 103:603-609, 2015. " 07/01/2015 - "Birth Defects Research (Part A) 103:589-596, 2015. "
5.	Chronic Obstructive Pulmonary Disease (COPD) 10/24/2022 - "For example, a 103/cm3 increase in the 6-day average UFP level was associated with a 25.4% increase in the TxB2 level in the COPD group but only an 11.2% increase in the non-COPD group. " 03/01/2005 - "A mean 87% increase in apoptosis of AEC and a 103% increase in T-lymphocyte apoptosis were found in COPD. "

Related Drugs and Biologics

1.	A 103 (A-103)
2.	Synucleins
3.	Biomarkers (Surrogate Marker)
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Solutions
6.	Messenger RNA (mRNA)
7.	Proteins (Proteins, Gene)
8.	Phosphates (Orthophosphate)
9.	Lipopolysaccharides
10.	Lipid A

Related Therapies and Procedures

1.	Stents
2.	Adjuvant Radiotherapy
3.	Segmental Mastectomy (Lumpectomy)
4.	Therapeutics
5.	Radiotherapy