4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride

has high affinity and selectivity for 5-HT3 receptors; structure given in first source

Also Known As:

4-amino-1-(6-chloro-2-pyridyl)-piperidine hydrochloride; SR 57227A; SR-57227A; 4-Piperidinamine, 1-(6-chloro-2-pyridinyl)-, monohydrochloride

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Chronic Pain 01/01/2022 - "These data suggested that SR 57227A is an effective alternative pain reliever to opioids that targets chronic pain."
2.	Pain (Aches) 01/01/2022 - "Here, we reported that SR 57227A, a serotonin type-3 receptor agonist, significantly reduced pain-like behaviors. " 01/01/2022 - "These data suggested that SR 57227A is an effective alternative pain reliever to opioids that targets chronic pain." 01/01/2022 - "Moreover, SR 57227A reduced pain-like behaviors of the formalin test, and restored reductions in paw withdrawal thresholds by acidic saline intramuscular injection and sciatic nerve ligation. " 01/01/2022 - "SR 57227A, a serotonin type-3 receptor agonist, as a candidate analgesic agent targeting nociplastic pain."

1.	Serotonin (5 Hydroxytryptamine)
2.	Formaldehyde (Formol)
3.	Opioid Analgesics (Opioids)
4.	Analgesics (Analgesic Drugs)