|1.||Noy, Noa: 4 articles (05/2008 - 04/2002)|
|2.||Chen, Nan-Nan: 3 articles (03/2015 - 01/2012)|
|3.||Liu, Jia: 3 articles (03/2015 - 01/2012)|
|4.||Kong, Qing-You: 3 articles (03/2015 - 01/2012)|
|5.||Chen, Xiao-Yan: 3 articles (03/2015 - 01/2012)|
|6.||Wu, Mo-Li: 3 articles (03/2015 - 01/2012)|
|7.||Li, Hong: 3 articles (03/2015 - 01/2012)|
|8.||Ishikawa, Minoru: 2 articles (07/2012 - 04/2010)|
|9.||Hashimoto, Yuichi: 2 articles (07/2012 - 04/2010)|
|10.||Itoh, Yukihiro: 2 articles (07/2012 - 04/2010)|
08/15/2006 - "Our findings also suggest that CRABP-II may be a potential therapeutic target for neuroblastoma."
08/15/2006 - "In contrast, de novo MycN protein synthesis was increased in CRABP-II-expressing neuroblastoma cells, thereby suggesting an autoregulatory loop that might exacerbate the effects of MycN gene amplification and affect the clinical outcome. "
08/15/2006 - "In addition, CRABP-II-transfected neuroblastoma cell lines show an increase in MycN protein levels resulting in increased cell motility. "
08/15/2006 - "Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma."
01/01/2002 - "Retinoid signalling and gene expression in neuroblastoma cells: RXR agonist and antagonist effects on CRABP-II and RARbeta expression."
|2.||Osteosarcoma (Osteogenic Sarcoma)
04/29/1994 - "In this study we have used reverse transcription (RT) and competitive polymerase chain reaction (cPCR) to investigate the effects of RA on CRABP-II expression levels in the human osteosarcoma cell line MG-63. "
04/29/1994 - "Thus, although 9-cis RA does not bind to CRABP-II, it induces CRABP-II expression more efficiently than at-RA in human osteosarcoma cells."
04/29/1994 - "Competitive PCR demonstrates that 9-cis retinoic acid induces cellular retinoic acid-binding protein-II more efficiently than all-trans retinoic acid in human osteosarcoma cells."
12/30/1992 - "In this study we have used a reverse transcription polymerase chain reaction (RT-PCR) to demonstrate that adult primary human osteoblasts and SaOS-2, a human osteosarcoma-derived cell line with osteoblastic properties, express cellular retinol-binding protein I (CRBP I), cellular retinoic acid-binding protein II (CRABP II), and very low levels of CRABP I. We also show that CRABP II is expressed in the adult liver, which does not express CRABP I. The results suggest that CRABP II is the important isoform in the adult bone as well as in the adult liver. "
05/30/2003 - "In this study, we excluded mutations within the complete coding region and the promoter of LMNA and the CRABP II gene in HIV-1 infected patients with lipodystrophy and also any correlation of the nucleotide polymorphism at codon 566 in exon 10 of LMNA with metabolic abnormalities. "
01/01/2007 - "Interestingly, the gene for CRABP-II is located on chromosome 1q21-23, which is a region that has been linked with disorders such as familial combined hyperlipidemia (FCHL), type 2 diabetes mellitus, and partial lipodystrophy, all of which are characterized by dyslipidemia. "
02/01/2003 - "Cellular Retinoic Acid Binding Protein-II gene (CRABP-II) (GDB 134819) is located on chromosome 1q21-23 and this region has been linked with related disorders such as Familial Combined Hyperlipidemia (FCHL), type 2 Diabetes Mellitus, and Lipodystrophy. "
09/01/1993 - "This study suggests that CRABP-II gene expression may be a more sensitive indicator of retinoid biologic activity in skin than are erythema or changes in epidermal morphology and differentiation."
10/01/1995 - "These data demonstrate that ROL application 1) produces trace erythema not significantly different from vehicle, whereas RA causes erythema; 2) induces epidermal thickening and enhances expression of CRABP-II and CRBP mRNAs and proteins as does RA; 3) causes marked accumulation of retinyl ester; and 4) does not significantly increase RA levels. "
09/01/1993 - "Although CD271 treatment did not lead to erythema or affect epidermal morphology, its ability to induce a marker of retinoid action (i.e., CRABP-II) was 70% the potency of all-trans retinoic acid. "
06/01/2014 - "We showed no detectable expressions of CRABP-II in normal pancreatic parenchyma, normal ductal epithelium, and chronic pancreatitis. "
06/01/2014 - "In this study, we studied the expression patterns of CRABP-II in pancreatic ductal adenocarcinoma (PDAC) compared with those in normal pancreas, chronic pancreatitis, and precancerous lesions. "
|1.||cellular retinoic acid binding protein II
|2.||Tretinoin (Retinoic Acid)
|3.||Carrier Proteins (Binding Protein)
|4.||retinoic acid receptor beta
|5.||Messenger RNA (mRNA)
|6.||cellular retinoic acid binding protein I
|7.||Proteins (Proteins, Gene)
|8.||Cellular Retinol-Binding Proteins