|1.||Lotan, R: 10 articles (10/2001 - 05/2000)|
|2.||Lotan, Reuben: 8 articles (01/2006 - 01/2002)|
|3.||Xu, X C: 7 articles (04/2001 - 05/2000)|
|4.||Fackler, Mary Jo: 5 articles (08/2010 - 12/2003)|
|5.||Sukumar, Saraswati: 5 articles (08/2010 - 12/2003)|
|6.||Argani, Pedram: 5 articles (09/2008 - 10/2003)|
|7.||Hong, W K: 5 articles (04/2001 - 05/2000)|
|8.||Ueoka, Hiroshi: 4 articles (09/2008 - 02/2005)|
|9.||Fujiwara, Keiichi: 4 articles (09/2008 - 02/2005)|
|10.||Xu, Xiao-Chun: 4 articles (08/2007 - 01/2002)|
|1.||Prostatic Neoplasms (Prostate Cancer)
01/01/2014 - "Also this study revealed that reverse correlation of RAR beta 2, ER alpha, PGR, and RGMA expressions with EZH2, SRC3, and AR expressions in prostate cancer tissues suggests that these genes are the target of EZH2. "
01/01/2014 - "The study demonstrated that H3K27me3 level was significantly enriched at the RAR beta 2, ER alpha, PGR, and RGMA promoter regions in prostate cancer tissues compared to normal tissues. "
01/01/2014 - "High H3K27me3 mark was significantly associated with decreased RAR beta 2, ER alpha, PGR and RGMA gene expressions in prostate cancer sample compared to the normal one. "
12/01/2011 - "Prognostic Value of Promoter Hypermethylation of Retinoic Acid Receptor Beta (RARB) and CDKN2 (p16/MTS1) in Prostate Cancer."
11/01/2009 - "Tumor suppressor genes retinoic acid receptor beta (RARbeta) and PDLIM4 are hypermethylated and silenced in prostate cancer (PCa) tissues and PCa cell lines compared to normal prostate cells. "
09/01/1993 - "A new synthetic retinoid analogue, adapalene (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid, CD271), which is relatively selective for retinoic acid receptor beta, was noted to be an effective comedolytic agent in the rhino mouse model and to have clinical efficacy against acne. "
04/01/2004 - "These studies demonstrate that aberrant methylation of RAR-beta is an early and common alteration in murine lung tumors induced by several environmentally relevant exposures."
02/01/1993 - "To study the possible role of RAR beta in growth control of epidermoid lung tumor-derived cells, transfectants expresing RAR beta were generated from nonexpressing epidermoid tumor-derived cell lines. "
10/01/2015 - "Human papillomavirus type 16 E7 oncoprotein upregulates the retinoic acid receptor-beta expression in cervical cancer cell lines and K14E7 transgenic mice."
02/01/2011 - "The RAR beta gene methylation did not differ based on the smoking status of patients in tumor tissue. "
02/01/2011 - "RAR beta gene methylation in tumor tissue was associated with clinical type (P < 0.05) and tumor stage (P < 0.05) significantly. "
|4.||Breast Neoplasms (Breast Cancer)
01/01/2005 - "The retinoic acid receptor beta 2 (RARbeta2) gene modulates proliferation and survival of cultured human breast cancer cells. "
01/01/2005 - "Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells."
11/01/2002 - "Retinoid, retinoic acid receptor beta and breast cancer."
07/20/1999 - "Elevated retinoic acid receptor beta(4) protein in human breast tumor cells with nuclear and cytoplasmic localization."
06/01/1999 - "The retinoic acid receptor beta (RARbeta), a putative tumor suppressor gene, has been reported to be poorly expressed in breast cancer. "
|5.||Lung Neoplasms (Lung Cancer)
11/28/2006 - "In the present study, we determined whether treatment with 9cRA has the potential to inhibit lung carcinogenesis by upregulating RAR-beta and down-regulating COX-2 expression in the A/J mouse lung cancer model. "
04/01/2004 - "These studies were extended to characterize the role of methylation of the RAR-beta gene in murine lung cancers. "
02/01/2011 - "The promoter methylation of p16, DAPK and RAR beta genes in 200 primary non-small cell lung cancers and the corresponding nonmalignant lung tissues were determined by methylation-specific PCR. "
06/24/2010 - "Pyrosequencing and quantitative RT-PCR experiments revealed time-dependent hypomethylation of D4Z4, NBL2, and LINE-1 repetitive DNA sequences; up-regulation of H19, IGF2, MAGE-A1, and MAGE-A3; activation of Wnt signaling; and hypermethylation of tumor suppressor genes such as RASSF1A and RAR-beta, which are frequently silenced in human lung cancers. "
01/01/2009 - "This is our aim when validating extensively research tools, focused on Retinoic Acid Receptor beta, whose major role in lung cancer is documented. "
|1.||retinoic acid receptor alpha
|4.||retinoic acid receptor beta
|5.||Tretinoin (Retinoic Acid)
|6.||retinoic acid receptor gamma
|8.||Messenger RNA (mRNA)
|9.||Retinoic Acid Receptors (Retinoic Acid Receptor)
|10.||Cyclin-Dependent Kinase Inhibitor p16
|2.||Drug Therapy (Chemotherapy)