|1.||Ling, Zhidong: 1 article (02/2005)|
|2.||Pipeleers, Daniel: 1 article (02/2005)|
|3.||Wang, Chen: 1 article (02/2005)|
|4.||Pavlovic, D: 1 article (03/2001)|
|5.||Pipeleers, D: 1 article (03/2001)|
|6.||Stangé, G: 1 article (03/2001)|
|7.||Hoorens, A: 1 article (03/2001)|
03/01/2001 - "Absence of IL-1-induced necrosis in rat alpha-cells or in human beta-cells is attributed to the cytokine's failure to generate NO in these preparations, not to their reduced sensitivity to NO: the NO donor GEA 3162 (15 min, 50-100 micromol/l) exerts a comparable necrotic effect in rat and human alpha- or beta-cells. "
02/01/2005 - "Exposure of rat purified beta-cells to streptozotocin (5 mM, 120 min) or to the nitric oxide donor GEA-3162 (GEA; 50 microM, 120 min) caused 80% necrosis within 24 h; at the end of this period, cellular insulin content was not significantly decreased, but cellular GABA content was reduced by 70%; when cultured at basal glucose (6 mM), the toxin-exposed cells did not discharge less insulin but released 80% less GABA in the period 8-24 h. "
|2.||Hypotension (Low Blood Pressure)
|2.||Nitric Oxide (Nitrogen Monoxide)
|5.||gamma-Aminobutyric Acid (GABA)