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MDL 201,404YA

inhibits neutrophil elastase

Also Known As:

CE 1037; CE-1037; MDL 201404YA; MDL-201,404YA; MDL-201404YA; bis(4-(2'-(carboxy-2'-methylpropylsulfonyl)phenyl)2,2'-(1,4-phenylene))diisobutyrate

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Butyrates: 2613
      - MDL 201,404YA: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - MDL 201,404YA: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Butyrates: 2613
      - MDL 201,404YA: 1

Experts

1.	Ohbayashi, Hiroyuki: 1 article (07/2002)

Related Diseases

1.	Chronic Obstructive Pulmonary Disease (COPD) 07/01/2002 - "In the application of chronic obstructive pulmonary disease therapy, the human neutrophil elastase inhibitors mainly focused upon include ONO-5046, MR-889, L-694,458, CE-1037, GW-311616 and TEI-8362 as the acyl-enzyme inhibitors; and ONO-6818, AE-3763, FK-706, ICI-200,880, ZD-0892 and ZD-8321 as the transition-state inhibitors. "

Related Drugs and Biologics

1.	Secretory Proteinase Inhibitory Proteins
2.	Enzyme Inhibitors (Inhibitors, Enzyme)
3.	N- ((3- (carboxymethyl)- 2- oxoimidazolidin- 1- yl)acetyl)- l- valyl- N- ((3S)- 1,1,1- trifluoro- 4- methyl- 2- oxopentan- 3- yl)- l- prolinamide
4.	ONO 6818
5.	TEI 8362
6.	ZD 0892
7.	ZD 8321
8.	DMP 777
9.	sivelestat
10.	midesteine

Related Therapies and Procedures

1.	Therapeutics