cytosolic-nuclear tumor promoter binding protein

binds tumor promoters such as tetradecanoylphorbol-13 acetate, teleocidins, aplysiatoxin & thapsigargin; MW 70 kDa existing in cytosolic fraction as a complex with the 90 kDa heat-shock protein; natural ligand is yakkasterone; amino acid sequence has been determined

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - cytosolic-nuclear tumor promoter binding protein: 1

Related Diseases

1.	Leukemia 03/01/1994 - "Among these analogs, compound 7 showed weak TPA-like activities in three biological tests: inhibition to protein kinase C and to cytosolic-nuclear tumor promoter-binding protein (CN-TPBP), and induction of differentiation of human promyelocytic leukemia cells (HL-60) to monocyte-like cells. "

Related Drugs and Biologics

1.	Protein Kinase C