neoandrographolide

structure in first source; isolated from Andrographis paniculata

Also Known As:

2(5H)-Furanone, 3-(2-((1R,4aS,5R,8aS)-5-((beta-D-glucopyranosyloxy)methyl)decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethyl)-

Networked: 10 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kumar, Kunal: 1 article (03/2022)
2.	Sharma, Rajani: 1 article (03/2022)
3.	Tanvi, Kumari: 1 article (03/2022)
4.	Liu, Ying: 1 article (12/2021)
5.	Liu, Yun: 1 article (12/2021)
6.	Wu, Xiang-Qi: 1 article (12/2021)
7.	Ye, Fei: 1 article (12/2021)
8.	Yin, Xiao-Rui: 1 article (12/2021)
9.	Yu, Fen-Fang: 1 article (12/2021)
10.	Zhang, Hong-Li: 1 article (12/2021)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 12/10/2019 - "Carbohydrate Modifications of Neoandrographolide for Improved Reactive Oxygen Species-Mediated Apoptosis through Mitochondrial Pathway in Colon Cancer."
2.	Myocardial Ischemia (Ischemic Heart Diseases) 12/01/2021 - "In the present study, we aimed to evaluate the cardioprotective effect of neoandrographolide (Neo) on myocardial ischemia/reperfusion injury (I/R) models and explore its possible mechanism. "
3.	Reperfusion Injury 12/01/2021 - "In the present study, we aimed to evaluate the cardioprotective effect of neoandrographolide (Neo) on myocardial ischemia/reperfusion injury (I/R) models and explore its possible mechanism. "
4.	Neoplasms (Cancer) 01/01/2020 - "Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth." 01/01/2014 - "A number of such compounds namely andrographolide (AG), neoandrographolide (NAG), and 14-deoxy-11,12-didehydroandrographolide (DDAG) have already attracted a great deal of attention due to their potential therapeutic effects in hard-to-treat diseases such as cancers and HIV. " 10/01/2021 - "AP consists of andrographolide (AD), 14-deoxy-11,12-didehydroandrographolide (DDAD), and neoandrographolide (NAD) as major diterpene lactones which has extremely bitter properties; therefore, AP is commonly called "King of bitters." AD, DDAD, and NAD are reported to possess therapeutic values such as antioxidant, immunostimulatory, hepatoprotective, anti-cancer, anti-inflammatory, anti-rheumatoidal, anti-malarial, anti-leishmanial, anti-fertility, anti-obesity, antipyretic, and antimicrobial attributes. "
5.	Gallstones (Gallstone) 01/01/2023 - "Dealkenylation of neoandrographolide, a phytochemical from Andrographis paniculata stimulates FXR (Farnesoid X Receptor) and enhances gallstone dissolution."

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Carbohydrates
3.	andrographolide
4.	14-deoxy-11,12-didehydroandrographolide
5.	Lactones
6.	Diterpenes
7.	14-deoxyandrographolide
8.	Phytochemicals
9.	Antipyretics
10.	Therapeutic Uses

Related Therapies and Procedures

1.	Oral Administration