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3,5-diiodothyropropionic acid

a cardiotonic thyroid hormone analog

Also Known As:

3,5-DITPA; DITPA cpd; Benzenepropanoic acid, 4-(4-hydroxyphenoxy)-3,5-diiodo-

Networked: 10 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Goldman, Steven: 5 articles (10/2011 - 01/2002)
2.	Bahl, Joseph J: 4 articles (10/2011 - 01/2002)
3.	Morkin, Eugene: 4 articles (11/2007 - 01/2002)
4.	Adamson, Cynthia: 2 articles (11/2007 - 12/2004)
5.	Spooner, Peter H: 2 articles (06/2002 - 01/2002)
6.	Ghanghas, Ravi: 1 article (03/2013)
7.	Jain, Suyog: 1 article (03/2013)
8.	Murthy, Mangala: 1 article (03/2013)
9.	Ramanand, Jaiprakash: 1 article (03/2013)
10.	Ramanand, Sunita: 1 article (03/2013)

Related Diseases

1.	Heart Failure 03/01/2013 - "Another compound, 3,5-diiodothyropropionic acid (DITPA), binds to both α- and β-type TRs with relatively low affinity and has been shown to be effective in heart failure (HF). " 12/01/2004 - "Screening of compounds for those that might be suitable for improving cardiac performance in heart failure led to the identification of 3,5-diiodothyropropionic acid (DITPA). " 06/01/2002 - "Clinical and experimental studies on the use of 3,5-diiodothyropropionic acid, a thyroid hormone analogue, in heart failure." 10/01/2011 - "The identification of 3,5-diiodothyropropionic acid (DITPA) that binds to both α- and β-type TRs with relatively low affinity was unique in that this analog improves left ventricular function in heart failure as well as lowers cholesterol. " 01/01/2002 - "Pilot studies on the use of 3,5-diiodothyropropionic acid, a thyroid hormone analog, in the treatment of congestive heart failure."
2.	Myocardial Infarction 02/01/1995 - "The purpose of this study was threefold: (1) to test the feasibility of using the V3(beta,beta) rabbit postinfarction model for the study of heart failure by characterizing the effects of chronic coronary artery occlusion on the left ventricle; (2) to determine whether the thyroid hormone analogue 3,5-diiodothyropropionic acid (DITPA) produces improvements in left ventricular function; and (3) to determine the effects of myocardial infarction and treatment with DITPA on MHC protein isoforms. "
3.	Infarction (Infarctions) 11/01/2000 - "The purpose of this study was to determine whether the thyroid hormone analogue, 3,5-diiodothyropropionic acid (DITPA), prevents abnormal Ca(2+)transport and expression of SR proteins associated with post-infarction heart failure. "
4.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2013 - "To assess the possible protective potential of MK-886 and 3,5-diiodothyropropionic acid DITPA against global myocardial ischemia reperfusion injury after heart transplantation. "
5.	Reperfusion Injury 01/01/2013 - "To assess the possible protective potential of MK-886 and 3,5-diiodothyropropionic acid DITPA against global myocardial ischemia reperfusion injury after heart transplantation. "

Related Drugs and Biologics

1.	Thyroid Hormones
2.	Protein Isoforms (Isoforms)
3.	Proteins (Proteins, Gene)
4.	Cholesterol
5.	Captopril (Capoten)
6.	MK-886

Related Therapies and Procedures

1.	Heart Transplantation (Grafting, Heart)