|1.||Wang, Zhiwei: 3 articles (12/2012 - 10/2011)|
|2.||Sarkar, Fazlul H: 3 articles (12/2012 - 10/2011)|
|3.||Gupta, Smiti V: 3 articles (12/2012 - 10/2011)|
|4.||Ji, Xiangming: 3 articles (12/2012 - 10/2011)|
|5.||Nakagawa, Kiyotaka: 3 articles (06/2010 - 09/2006)|
|6.||Miyazawa, Teruo: 3 articles (06/2010 - 09/2006)|
|7.||Geamanu, Andreea: 2 articles (12/2012 - 10/2011)|
|8.||Sookwong, Phumon: 2 articles (06/2010 - 08/2008)|
|9.||Shibata, Akira: 2 articles (06/2010 - 08/2008)|
|10.||Mo, Huanbiao: 2 articles (05/2009 - 04/2007)|
01/01/2009 - "This concentration was observed with the oral dose (100 mg/kg) of delta-tocotrienol which inhibited tumor growth by 80% in our previous studies. "
01/01/2014 - "Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells."
10/01/2011 - "Treatment with delta-tocotrienol resulted in a dose and time dependent inhibition of cell growth, cell migration, tumor cell invasiveness, and induction of apoptosis. "
01/01/2009 - "Interestingly, delta-tocotrienol was 10-fold more concentrated in the pancreas than in the tumor. "
01/01/2009 - "When mice were fed delta-tocotrienol for 6 weeks, the concentration in tumor tissue was 41 +/- 3.5 nmol/g. "
|2.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/01/2011 - "Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation."
10/01/2011 - "These results suggest that down-regulation of Notch-1, via inhibition of NF-κB signaling pathways by delta-tocotrienol, could provide a potential novel approach for prevention of tumor progression in non-small cell lung cancer."
10/01/2011 - "The objective of this study was to investigate whether delta-tocotrienol, a naturally occurring isoform of Vitamin E, inhibits non-small cell lung cancer cell growth via Notch signaling. "
07/01/2012 - "Delta-tocotrienol augments cisplatin-induced suppression of non-small cell lung cancer cells via inhibition of the Notch-1 pathway."
|3.||Breast Neoplasms (Breast Cancer)
09/01/2008 - "Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product."
09/01/2008 - "To the best of our knowledge, this study was the first to reveal that the target of cell proliferative inhibitory action of delta-tocotrienol in a model estrogen receptor-negative human breast cancer cell line MDA-MB-231 is mediated by the loss of cyclin D1 and associated suppression of site-specific Rb phosphorylation, suggesting its future development and use as an anticancer agent."
01/01/2004 - "Like VES, alpha-TEA and delta-tocotrienol induced estrogen-nonresponsive MDA-MB-435 and estrogen-responsive MCF-7 human breast cancer cells to undergo high levels of apoptosis in a concentration- and time-dependent fashion. "
01/01/2004 - "Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells."
|4.||Lung Neoplasms (Lung Cancer)
12/01/2012 - "Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells."
12/01/2012 - "In our study, using miRNA microarray, we observed that downregulation of the Notch-1 pathway, by delta-tocotrienol, correlated with upregulation of miR-34a, in nonsmall cell lung cancer cells (NSCLC). "
|5.||Colonic Neoplasms (Colon Cancer)
11/01/2012 - "[Experimental study on delta-tocotrienol inhibits the Wnt pathway in the colon cancer cell SW620]."
11/01/2012 - "delta-tocotrienol has a significant proliferation inhibition effect on the colon cancer cells SW620,under delta-tocotrienol treated, SW620 cell inhibition rate is 70.43%. "
11/01/2012 - "To adopt the MTT method, found the effects of diverse doses of delta-tocotrienol on colon cancer cells SW620. "
11/01/2012 - "Based on the antitumor function of the delta-tocotrienol, shed light on the relationship between the proliferation inhibition effect of delta-tocotrienol on human colon cancer cells SW620 with Wnt signal pathway. "
11/01/2012 - "The proliferation inhibition effect of delta-tocotrienol on colon cancer cell may correlate with the ability of delta-tocotrienol to downregulate the expression levels of wnt-1, beta-catenin, c-jun, cylin D1 in the Wnt signal pathway."