gomisin D

a lignan from Schizandra chinensis

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

1.	Liver Cirrhosis (Hepatic Cirrhosis) 04/30/2023 - "A male BALB/c mouse liver fibrosis model was established to comfirm gomisin D (especially in 50 mg/kg) could improve liver fibrosis by inhibiting HSCs activation. " 04/30/2023 - "Gomisin D alleviates liver fibrosis through targeting PDGFRβ in hepatic stellate cells." 04/30/2023 - "Mechanically, gomisin D regulated PDGF-BB/PDGFRβ signaling pathway by targeting PDGFRβ, further more inhibited HSC activation, subsequently inhibited inflammatory factors, ultimately improved CCl4-induced liver fibrosis. "
2.	Fibrosis (Cirrhosis) 04/30/2023 - "In this study, the effect of gomisin D on hepatic fibrosis was evaluated in vivo and vitro. " 04/30/2023 - "However, whether gomisin D has anti-fibrosis effects through targeting PDGFRβ remained unclear. " 04/30/2023 - "Overall, gomisin D could inhibit HSC proliferation and activation, promote HSC apoptosis, and alleviate CCl4-induced hepatic fibrosis by targeting PDGFRβ and regulating PDGF-BB/PDGFRβ signaling pathway. "
3.	Acquired Immunodeficiency Syndrome (AIDS) 08/01/2014 - "The contents of the functional ingredients includes chisandrin, gomisin D, gomisin J, schisandrol B, angeloylgomisin H, angeloylgomisin Q, gomisin G, schisantherin A, deoxyschisandrin, schisandrin B, schisandrin C, 5-HMF, total aids and total sugars. "