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phthalide

Networked: 17 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - phthalide: 17

Experts

1.	Du, Jun-Rong: 2 articles (11/2020 - 01/2008)
2.	Cao, Zhengyu: 1 article (10/2022)
3.	Hu, Yixin: 1 article (10/2022)
4.	Tan, Liaoxi: 1 article (10/2022)
5.	Xi, Chuchu: 1 article (10/2022)
6.	Yang, Zhao: 1 article (10/2022)
7.	Zhang, Chunlei: 1 article (10/2022)
8.	Zhang, Xinyi: 1 article (10/2022)
9.	Zhao, Fang: 1 article (10/2022)
10.	Meng, Fancheng: 1 article (07/2022)

Related Diseases

1.	Malaria 01/01/2023 - "Phthalide derivatives as dihydrofolate reductase inhibitors for malaria: molecular docking and molecular dynamics studies."
2.	Leukemia 03/01/2011 - "The structure activity relationship (SAR) study showed that the presence of a phthalide group in bibenzyls, an alpha-methylene-gamma-lactone in germacrane-type sesquiterpenoids, and beta-hydroxycarbonyl in pinguisane-type sesquiterpenoids play an important role in providing cytotoxic activity against both human promyelocytic leukemia (HL-60) and human pharyngeal squamous carcinoma (KB) cell lines. "
3.	Ischemia 01/01/2008 - "Previous studies have demonstrated that Z-Ligustilide (LIG), a characterized phthalide constituent present in numerous medical Umbelliferae plants, has significant neuroprotective effects in transient forebrain ischemia and permanent cerebral focal ischemia. "
4.	Fibrosis (Cirrhosis) 06/01/2018 - "In the current study, we evaluated the cytotoxicity of butylidenephthalide (BP), a major phthalide ingredient of Angelica sinensis, in fibrotic buccal mucosal fibroblasts (fBMFs) as well as various myofibroblast hallmarks, including the phenotypical characteristics and fibrosis-related markers. "
5.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/01/2011 - "The structure activity relationship (SAR) study showed that the presence of a phthalide group in bibenzyls, an alpha-methylene-gamma-lactone in germacrane-type sesquiterpenoids, and beta-hydroxycarbonyl in pinguisane-type sesquiterpenoids play an important role in providing cytotoxic activity against both human promyelocytic leukemia (HL-60) and human pharyngeal squamous carcinoma (KB) cell lines. "

Related Drugs and Biologics

1.	Neuroprotective Agents
2.	Lactones
3.	ligustilide
4.	Sesquiterpenes
5.	Folic Acid Antagonists
6.	Bibenzyls
7.	butylidenephthalide
8.	isoquinoline
9.	3-n-butylphthalide (butylphthalide)
10.	Fluconazole (Zonal)

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Aftercare (After-Treatment)