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sipatrigine

a glutamate release inhibitor which protects against focal cerebral ischemic damage
Also Known As:
4-amino-2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)pyrimidine; 619C89; BW 619C89; BW-619C89; BW619C89
Networked: 22 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tsai, Shih-Jen: 1 article (01/2008)
2. Callaway, J K: 1 article (07/2004)
3. Jarrott, B: 1 article (07/2004)
4. Giardina, S F: 1 article (07/2004)
5. Beart, P M: 1 article (07/2004)
6. Krstew, E K: 1 article (07/2004)
7. Castillo-Melendez, M: 1 article (07/2004)
8. Hainsworth, Atticus H: 1 article (02/2003)
9. Lambert, David G: 1 article (02/2003)
10. Richard Green, A: 1 article (02/2003)

Related Diseases

1. Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
2. Brain Ischemia (Cerebral Ischemia)
3. Stroke (Strokes)
4. Ischemia
5. Brain Injuries (Brain Injury)

Related Drugs and Biologics

1. Glutamic Acid (Glutamate)
2. Sodium Channels (Sodium Channel)
3. lamotrigine (Lamictal)
4. Sodium Channel Blockers (Potassium Sparing Diuretics)
5. CNS 1237
6. sipatrigine
7. N-Methylaspartate (NMDA)
8. Endothelin-1 (Endothelin 1)
9. Glutamate Receptors (Glutamate Receptor)
10. Platelet Activating Factor

Related Therapies and Procedures

1. Intravenous Infusions
2. Oral Administration