protein kinase C eta

05/03/2007 - "The level of PKC-eta expressed correlates with the degree of phorbol-12-myristate-13-acetate (PMA)-induced proliferation of two glioblastoma cell lines, U-1242 MG and U-251 MG. Normally, U-1242 cells do not express PKC-eta, and PMA inhibits their proliferation. "
04/01/2005 - "PKC eta as a therapeutic target in glioblastoma multiforme."
12/02/2004 - "PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways."
01/18/2007 - "In this study, we investigated the efficacy of rapamycin in inhibiting cell proliferation in two glioblastoma cell lines U-251MG (PKC-eta expressing) and U-1242MG (PKC-eta deficient) following PKC-eta activation. "
01/01/2002 - "In the present study of several glioblastoma cell lines, we investigated the role of PKC-eta in preventing UV- and gamma-irradiation-induced apoptosis and in caspase-dependent signaling pathways that mediate cell death. "

08/01/2001 - "The purpose of this study was to examine whether PKC eta is altered, in expression or localization, in human breast cancer. "
08/01/2001 - "Altered expression and localization of PKC eta in human breast tumors."
08/01/2001 - "Paraffin sections of 49 in situ breast lesions, 29 invasive breast tumors, and nine normal breast biopsies were examined for PKC eta expression by immunohistochemistry. "
12/09/2000 - "We previously showed that the induction of novel PKC eta isozyme by PKC activators correlated with their ability to protect MCF-7 breast cancer cells against TNF cytotoxicity. "
01/01/2019 - "Protein kinase C-eta (PKCη) is considered an anti-apoptotic kinase, which promotes cell survival and chemoresistance in several cancers, including breast cancer. "

03/01/2008 - "We study the association between three protein kinase C, eta gene polymorphisms (+8134C/T, rs912620, rs959728), and susceptibility to rheumatoid arthritis. "
03/01/2008 - "Furthermore, the lower expression of this gene in rheumatoid arthritis patients comparing to healthy controls suggests that protein kinase C, eta could be associated with the patho-physiologic mechanism of rheumatoid arthritis."
03/01/2008 - "Our results showed no significant association or linkage between the protein kinase C, eta polymorphisms, and rheumatoid arthritis. "
05/01/2007 - "Progressive and concordant expression of PKC-eta and iNOS phenotypes in monocytes from patients with rheumatoid arthritis: association with disease severity."
03/01/2008 - "This study shows that protein kinase C, eta gene is not a Rheumatoid Arthritis major susceptibility genetic factor in the French Caucasian population. "

03/01/2008 - "This study shows that protein kinase C, eta gene is not a Rheumatoid Arthritis major susceptibility genetic factor in the French Caucasian population. "

09/01/2003 - "The major result is a clear correlation of PKC eta expression with tumor progression. "
08/01/2001 - "These results demonstrate that quantitative and qualitative alterations in PKC eta occur in human breast cancers."
08/01/2001 - "The invasive tumors which possessed high PKC eta staining were associated with positive lymph node status. "
11/01/2000 - "Moreover, changes in neither PKC-eta expression, PKC activity nor chemoresistance induced by a particular drug in an individual tumor necessarily predicted the same reaction in another tumor to this agent. "
01/01/1998 - "Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC eta with MDR1, MRP and LRP gene expression."