WR 33063

structure given in first source; RN given refers to parent compound

Also Known As:

WR 33063, (+)-isomer; WR 33063, (+-)-isomer; WR 33063, (-)-isomer; WR 33063, citrate; WR 33063, hydrochloride, (+)-isomer; WR 33063, hydrochloride, (+-)-isomer; WR 33063, hydrochloride, (-)-isomer; WR 33063, hydrochoride; WR 33063, tartrate; WR-33,063; WR-33063

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Malaria 02/01/1973 - "In all, 52 men received WR 33063 in tolerance trials, and 59 men with experimental malaria and one man with clinical malaria were treated with WR 33063." 02/01/1973 - "The African Uganda I strain of chloroquine-responsive malaria was even more responsive to WR 33063; all of six men who received 1.6 g in four divided doses for 6 days were cured, and all of three men who received this same dosage for 3 days were cured. " 02/01/1973 - "WR 33063 (3-bromo-10-[alpha-hydroxy-beta-(n, n-diheptylamino)ethyl]-phenanthrene hydrochloride) and WR 30090 (6,8-dichloro-2,3,4-dichlorphenyl-di-n-butylaminoethyl-4- quinolinemethanol hydrochloride) were tested for suppressive prophylactic effect on induced malaria in nonimmune volunteers living in an area where malaria is not naturally transmitted. " 02/01/1973 - "Prophylactic activity of a phenanthrene methanol (WR 33063) and a quinoline methanol (WR 30090) in human malaria."
2.	Falciparum Malaria (Plasmodium falciparum Malaria) 07/01/1974 - "Preliminary study of WR 33063 in the treatment of falciparum malaria in northeast Thailand." 02/01/1973 - "Treatment of falciparum malaria from Vietnam with a phenanthrene methanol (WR 33063) and a quinoline methanol (WR 30090)."
3.	Infections 02/01/1973 - "WR 33063 did not interfere with early development of infection, but WR 30090 given for 8 weeks provided suppressive cures in 20 of 26 men. "
4.	Acute malaria 02/01/1973 - "A phenanthrene methanol (WR 33063) for treatment of acute malaria."

Related Drugs and Biologics

1.	Chloroquine (Aralen)
2.	Methanol (Carbinol)
3.	phenanthrene
4.	quinoline
5.	WR 30090