alpha- amino- 3- hydroxy- 5- tert- butyl- 4- isoxazolepropionate

a glutamate agonist

Also Known As:

2-amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propionic acid; 2-amino-3-(hydroxy-5-tert-butylisoxazol-yl)propionic acid; ATPA-tert; alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate, (+-)-isomer

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Isoxazoles: 155
      - alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate: 1
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate: 1

Related Diseases

1.	Seizures (Absence Seizure) 07/15/1993 - "Surprisingly, during this "silent phase" the susceptibility of mice to alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate (ATPA) and kainate seizures and the magnitude of monosynaptic reflexes mediated by non-N-methyl-D-aspartate (NMDA) mechanisms were enhanced. "

Related Drugs and Biologics

1.	N-Methylaspartate (NMDA)
2.	Kainic Acid (Kainate)