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human AF-2 protein

AF-2 protein is a nuclear antigen conserved between fission yeast & man whose distribution is cell-cycle dependent; this permits the quantitative analysis of mitotic & early G1 cells by using the monoclonal antibodies against the antigen; the AF-2 domain is an activation domain of nuclear receptors used to recruit coregulator complexes; has been sequenced
Also Known As:
AF-2 protein, human; AF-2 nuclear antigen, human
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